Appendix cancer: Difference between revisions
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File:Appendiceal_carcinoid_1.JPG|Appendiceal carcinoid tumor | {{Infobox medical condition | ||
File:Appendix_neoplasms_by_incidence_and_prognosis.png|Appendix neoplasms by incidence and prognosis | | name = Appendix cancer | ||
File:Histopathology_of_appendiceal_carcinoid.jpg|Histopathology of appendiceal carcinoid | | image = [[File:Appendiceal_carcinoid_1.JPG|left|thumb|Appendiceal carcinoid]] | ||
File:Histopathology_of_low-grade_appendiceal_mucinous_neoplasm.jpg|Histopathology of low-grade appendiceal mucinous neoplasm | | caption = Histopathological image of an appendiceal carcinoid | ||
| field = [[Oncology]] | |||
| symptoms = [[Abdominal pain]], [[bloating]], [[changes in bowel habits]] | |||
| complications = [[Peritoneal carcinomatosis]], [[bowel obstruction]] | |||
| onset = Typically in [[adulthood]] | |||
| duration = Variable | |||
| types = [[Carcinoid tumor]], [[mucinous adenocarcinoma]], [[goblet cell carcinoid]] | |||
| causes = Unknown | |||
| risks = Family history, [[smoking]], [[obesity]] | |||
| diagnosis = [[CT scan]], [[MRI]], [[biopsy]] | |||
| differential = [[Appendicitis]], [[ovarian cancer]], [[colorectal cancer]] | |||
| treatment = [[Surgery]], [[chemotherapy]], [[radiation therapy]] | |||
| prognosis = Depends on stage and type | |||
| frequency = Rare | |||
}} | |||
[[File:Appendix_neoplasms_by_incidence_and_prognosis.png|Appendix neoplasms by incidence and prognosis|thumb|left]] | |||
[[File:Histopathology_of_appendiceal_carcinoid.jpg|Histopathology of appendiceal carcinoid|thumb|left]] | |||
[[File:Histopathology_of_low-grade_appendiceal_mucinous_neoplasm.jpg|Histopathology of low-grade appendiceal mucinous neoplasm|thumb|left]] | |||
Appendix cancer is a rare type of cancer that occurs in the [[appendix]], a small, tube-shaped pouch attached to the large intestine. This type of cancer can be challenging to diagnose due to its rarity and the non-specific nature of its symptoms. | Appendix cancer is a rare type of cancer that occurs in the [[appendix]], a small, tube-shaped pouch attached to the large intestine. This type of cancer can be challenging to diagnose due to its rarity and the non-specific nature of its symptoms. | ||
==Types== | ==Types== | ||
Appendix cancer can be classified into several types based on the type of cells involved: | Appendix cancer can be classified into several types based on the type of cells involved: | ||
* '''[[Carcinoid tumors]]''': These are the most common type of appendix cancer and originate from the hormone-producing cells of the appendix. They are often slow-growing and may not cause symptoms until they are advanced. | * '''[[Carcinoid tumors]]''': These are the most common type of appendix cancer and originate from the hormone-producing cells of the appendix. They are often slow-growing and may not cause symptoms until they are advanced. | ||
* '''[[Adenocarcinoma]]''': This type of cancer arises from the glandular cells lining the appendix. It is more aggressive than carcinoid tumors and can spread to other parts of the body. | * '''[[Adenocarcinoma]]''': This type of cancer arises from the glandular cells lining the appendix. It is more aggressive than carcinoid tumors and can spread to other parts of the body. | ||
* '''[[Mucinous adenocarcinoma]]''': This subtype is characterized by the production of mucin, a jelly-like substance. It can lead to a condition known as [[pseudomyxoma peritonei]], where mucin accumulates in the abdominal cavity. | * '''[[Mucinous adenocarcinoma]]''': This subtype is characterized by the production of mucin, a jelly-like substance. It can lead to a condition known as [[pseudomyxoma peritonei]], where mucin accumulates in the abdominal cavity. | ||
* '''[[Signet ring cell carcinoma]]''': A rare and aggressive form of adenocarcinoma, signet ring cell carcinoma is named for the appearance of the cancer cells under a microscope. | * '''[[Signet ring cell carcinoma]]''': A rare and aggressive form of adenocarcinoma, signet ring cell carcinoma is named for the appearance of the cancer cells under a microscope. | ||
* '''[[Goblet cell carcinoid]]''': This is a hybrid tumor with features of both adenocarcinoma and carcinoid tumors. It tends to be more aggressive than typical carcinoid tumors. | * '''[[Goblet cell carcinoid]]''': This is a hybrid tumor with features of both adenocarcinoma and carcinoid tumors. It tends to be more aggressive than typical carcinoid tumors. | ||
==Symptoms== | ==Symptoms== | ||
Symptoms of appendix cancer can be vague and may include: | Symptoms of appendix cancer can be vague and may include: | ||
* Abdominal pain or discomfort | * Abdominal pain or discomfort | ||
* Bloating or a feeling of fullness | * Bloating or a feeling of fullness | ||
| Line 30: | Line 36: | ||
* Unexplained weight loss | * Unexplained weight loss | ||
* Nausea and vomiting | * Nausea and vomiting | ||
In some cases, appendix cancer is discovered incidentally during surgery for another condition, such as [[appendicitis]]. | In some cases, appendix cancer is discovered incidentally during surgery for another condition, such as [[appendicitis]]. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of appendix cancer typically involves a combination of: | Diagnosis of appendix cancer typically involves a combination of: | ||
* [[Imaging studies]]: Such as [[CT scan]]s or [[MRI]]s to visualize the appendix and surrounding tissues. | * [[Imaging studies]]: Such as [[CT scan]]s or [[MRI]]s to visualize the appendix and surrounding tissues. | ||
* [[Biopsy]]: A sample of tissue may be taken to confirm the diagnosis and determine the type of cancer. | * [[Biopsy]]: A sample of tissue may be taken to confirm the diagnosis and determine the type of cancer. | ||
* [[Blood tests]]: To check for tumor markers and assess overall health. | * [[Blood tests]]: To check for tumor markers and assess overall health. | ||
==Treatment== | ==Treatment== | ||
Treatment options for appendix cancer depend on the type and stage of the cancer and may include: | Treatment options for appendix cancer depend on the type and stage of the cancer and may include: | ||
* '''[[Surgery]]''': The primary treatment for localized appendix cancer is surgical removal of the appendix, often along with part of the colon and surrounding tissues. | * '''[[Surgery]]''': The primary treatment for localized appendix cancer is surgical removal of the appendix, often along with part of the colon and surrounding tissues. | ||
* '''[[Chemotherapy]]''': Used to kill cancer cells or shrink tumors, especially in cases where the cancer has spread. | * '''[[Chemotherapy]]''': Used to kill cancer cells or shrink tumors, especially in cases where the cancer has spread. | ||
* '''[[Cytoreductive surgery]] and [[hyperthermic intraperitoneal chemotherapy]] (HIPEC)''': A specialized treatment for pseudomyxoma peritonei, involving the surgical removal of tumors followed by the direct application of heated chemotherapy to the abdominal cavity. | * '''[[Cytoreductive surgery]] and [[hyperthermic intraperitoneal chemotherapy]] (HIPEC)''': A specialized treatment for pseudomyxoma peritonei, involving the surgical removal of tumors followed by the direct application of heated chemotherapy to the abdominal cavity. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for appendix cancer varies widely depending on the type and stage of the cancer. Carcinoid tumors generally have a better prognosis than adenocarcinomas. Early detection and treatment are crucial for improving outcomes. | The prognosis for appendix cancer varies widely depending on the type and stage of the cancer. Carcinoid tumors generally have a better prognosis than adenocarcinomas. Early detection and treatment are crucial for improving outcomes. | ||
==See also== | |||
== | |||
* [[Appendicitis]] | * [[Appendicitis]] | ||
* [[Gastrointestinal cancer]] | * [[Gastrointestinal cancer]] | ||
* [[Neuroendocrine tumor]] | * [[Neuroendocrine tumor]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
Latest revision as of 16:51, 4 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics
| Appendix cancer | |
|---|---|
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Abdominal pain, bloating, changes in bowel habits |
| Complications | Peritoneal carcinomatosis, bowel obstruction |
| Onset | Typically in adulthood |
| Duration | Variable |
| Types | Carcinoid tumor, mucinous adenocarcinoma, goblet cell carcinoid |
| Causes | Unknown |
| Risks | Family history, smoking, obesity |
| Diagnosis | CT scan, MRI, biopsy |
| Differential diagnosis | Appendicitis, ovarian cancer, colorectal cancer |
| Prevention | N/A |
| Treatment | Surgery, chemotherapy, radiation therapy |
| Medication | N/A |
| Prognosis | Depends on stage and type |
| Frequency | Rare |
| Deaths | N/A |
Appendix cancer is a rare type of cancer that occurs in the appendix, a small, tube-shaped pouch attached to the large intestine. This type of cancer can be challenging to diagnose due to its rarity and the non-specific nature of its symptoms.
Types[edit]
Appendix cancer can be classified into several types based on the type of cells involved:
- Carcinoid tumors: These are the most common type of appendix cancer and originate from the hormone-producing cells of the appendix. They are often slow-growing and may not cause symptoms until they are advanced.
- Adenocarcinoma: This type of cancer arises from the glandular cells lining the appendix. It is more aggressive than carcinoid tumors and can spread to other parts of the body.
- Mucinous adenocarcinoma: This subtype is characterized by the production of mucin, a jelly-like substance. It can lead to a condition known as pseudomyxoma peritonei, where mucin accumulates in the abdominal cavity.
- Signet ring cell carcinoma: A rare and aggressive form of adenocarcinoma, signet ring cell carcinoma is named for the appearance of the cancer cells under a microscope.
- Goblet cell carcinoid: This is a hybrid tumor with features of both adenocarcinoma and carcinoid tumors. It tends to be more aggressive than typical carcinoid tumors.
Symptoms[edit]
Symptoms of appendix cancer can be vague and may include:
- Abdominal pain or discomfort
- Bloating or a feeling of fullness
- Changes in bowel habits
- Unexplained weight loss
- Nausea and vomiting
In some cases, appendix cancer is discovered incidentally during surgery for another condition, such as appendicitis.
Diagnosis[edit]
Diagnosis of appendix cancer typically involves a combination of:
- Imaging studies: Such as CT scans or MRIs to visualize the appendix and surrounding tissues.
- Biopsy: A sample of tissue may be taken to confirm the diagnosis and determine the type of cancer.
- Blood tests: To check for tumor markers and assess overall health.
Treatment[edit]
Treatment options for appendix cancer depend on the type and stage of the cancer and may include:
- Surgery: The primary treatment for localized appendix cancer is surgical removal of the appendix, often along with part of the colon and surrounding tissues.
- Chemotherapy: Used to kill cancer cells or shrink tumors, especially in cases where the cancer has spread.
- Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC): A specialized treatment for pseudomyxoma peritonei, involving the surgical removal of tumors followed by the direct application of heated chemotherapy to the abdominal cavity.
Prognosis[edit]
The prognosis for appendix cancer varies widely depending on the type and stage of the cancer. Carcinoid tumors generally have a better prognosis than adenocarcinomas. Early detection and treatment are crucial for improving outcomes.