Dexbrompheniramine: Difference between revisions

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{{Short description|An antihistamine used to treat allergic conditions}}
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| image_caption = Chemical structure of Dexbrompheniramine
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{{intro}}
'''Dexbrompheniramine''' is an [[antihistamine]] medication used primarily to treat [[allergic conditions]] such as [[hay fever]] and [[urticaria]]. It is a member of the [[alkylamine]] class of antihistamines and is known for its ability to relieve symptoms such as [[sneezing]], [[itching]], and [[runny nose]].
Brompheniramine and chlorpheniramine maleate are first generation antihistamines that are widely used to treat symptoms of allergic rhinitis and the common cold.


{{livtox}}
==Pharmacology==
Clinically apparent liver injury from brompheniramine or chlorpheniramine must be exceeding rare, if it occurs at all.
Dexbrompheniramine works by blocking the action of [[histamine]], a substance in the body that causes allergic symptoms. As an [[H1 receptor antagonist]], it prevents histamine from binding to its receptors, thereby reducing the allergic response.


{{moa}}
==Uses==
Brompheniramine (brome" fen ir' a meen) and chlorpheniramine (klor" fen ir' a meen) are first generation antihistamines that are used widely in the therapy of the symptoms of sneezing, cough, runny note, watery eyes and itching.  They are similar in chemical structure and constitute the alkylamine class of antihistamines.  They are probably the most commonly used over-the-counter antihistamines, being present alone or in combination with other agents in more than 1000 products used for the symptoms of the common cold, sinusitis, urticaria and hay fever.  Both agents are also available as their dextrorotatory isomers, dexbrompheniramine and dexchlorpheniramine, which have similar profiles of action and side effects. 
Dexbrompheniramine is used to treat a variety of allergic conditions, including:
* [[Allergic rhinitis]]
* [[Conjunctivitis]]
* [[Chronic urticaria]]


{{brand}}
==Side Effects==
Common brand name preparations include Chlor-Trimeton, Dimetane, Drixoral and Durahist, and most are available without a prescription and in combination with sympathomimetic agents (such as pseudoephedrine or phenylephrine) or analgesics or both. 
Common side effects of dexbrompheniramine include:
* [[Drowsiness]]
* [[Dry mouth]]
* [[Dizziness]]


{{dose}}
Less common side effects may include:
The typical oral dose in adults is 2 to 4 mg three or four times a day. 
* [[Nausea]]
* [[Headache]]
* [[Nervousness]]


{{se}}
==Dosage==
Common side effects include sedation, impairment of motor function, confusion, dizziness, blurred vision, dry mouth and throat, palpitations, tachycardia, abdominal distress, constipation and headache.  Antihistamines can worsen urinary retention and glaucoma.
The dosage of dexbrompheniramine varies depending on the condition being treated and the patient's response to the medication. It is important to follow the prescribed dosage and consult a healthcare provider for any adjustments.
 
{{antihistamines}}
==Mechanism of Action==
{{coststubd}}
Dexbrompheniramine acts as a competitive antagonist at the [[histamine H1 receptor]]. By inhibiting the binding of histamine, it reduces the symptoms associated with allergic reactions.
 
==History==
Dexbrompheniramine was developed as a derivative of [[brompheniramine]], with the goal of providing effective relief from allergic symptoms with potentially fewer side effects.
 
==Related pages==
* [[Antihistamine]]
* [[Allergy]]
* [[Histamine]]
 
[[Category:Antihistamines]]
[[Category:Alkylamines]]

Revision as of 11:27, 15 February 2025

An antihistamine used to treat allergic conditions


Dexbrompheniramine
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Dexbrompheniramine is an antihistamine medication used primarily to treat allergic conditions such as hay fever and urticaria. It is a member of the alkylamine class of antihistamines and is known for its ability to relieve symptoms such as sneezing, itching, and runny nose.

Pharmacology

Dexbrompheniramine works by blocking the action of histamine, a substance in the body that causes allergic symptoms. As an H1 receptor antagonist, it prevents histamine from binding to its receptors, thereby reducing the allergic response.

Uses

Dexbrompheniramine is used to treat a variety of allergic conditions, including:

Side Effects

Common side effects of dexbrompheniramine include:

Less common side effects may include:

Dosage

The dosage of dexbrompheniramine varies depending on the condition being treated and the patient's response to the medication. It is important to follow the prescribed dosage and consult a healthcare provider for any adjustments.

Mechanism of Action

Dexbrompheniramine acts as a competitive antagonist at the histamine H1 receptor. By inhibiting the binding of histamine, it reduces the symptoms associated with allergic reactions.

History

Dexbrompheniramine was developed as a derivative of brompheniramine, with the goal of providing effective relief from allergic symptoms with potentially fewer side effects.

Related pages