Punicalagin: Difference between revisions

Latest revision as of 04:04, 13 February 2025

Punicalagin[edit]

Punicalagin is a type of ellagitannin, a class of polyphenols found in certain plants. It is most notably present in pomegranates (Punica granatum), from which it derives its name. Punicalagin is known for its potential antioxidant properties and is a subject of interest in nutritional science and pharmacology.

Chemical Structure[edit]

Punicalagin is a large, water-soluble molecule that consists of a gallagic acid and ellagic acid moiety linked to a glucose core. It exists in two isomeric forms, alpha and beta, which differ in the orientation of the hydroxyl groups. The chemical formula for punicalagin is C₄₈H₂₈O₃₀.

Sources[edit]

Punicalagin is primarily found in the peel and juice of pomegranates. It is also present in smaller amounts in other fruits such as walnuts, chestnuts, and certain types of berries.

Biological Activity[edit]

Punicalagin is studied for its potential health benefits, particularly its antioxidant and anti-inflammatory properties. It is believed to help in reducing oxidative stress and may have a role in cardiovascular health.

Metabolism[edit]

Upon ingestion, punicalagin is hydrolyzed in the gut to release ellagic acid, which is further metabolized by the microbiota to produce urolithins. These metabolites are thought to be responsible for the biological effects attributed to punicalagin.

Potential Health Benefits[edit]

Research suggests that punicalagin may have several health benefits, including:

Antioxidant Effects: It helps in neutralizing free radicals and reducing oxidative damage to cells.
Anti-inflammatory Effects: It may reduce inflammation by inhibiting the production of pro-inflammatory cytokines.
Cardiovascular Health: Punicalagin may improve blood pressure and cholesterol levels, contributing to heart health.

Related Pages[edit]

@@ Line 1: / Line 1: @@
-'''Punicalagin''' is a type of [[ellagitannin]], a large group of [[polyphenols]] found in certain types of fruits and nuts. It is most notably found in [[pomegranates]], from which it derives its name (Punica is the genus name for the pomegranate). Punicalagin is the largest molecule found intact in rat plasma after oral ingestion and health effects have been attributed to its antioxidant activity.
+== Punicalagin ==
-==Chemical Structure==
+[[File:Punicalagin1.png|thumb|right|Chemical structure of Punicalagin]]
-Punicalagin is a large polyphenol compound. It is a type of [[tannin]] and is considered the largest of the hydrolyzable tannins. Its structure includes a pair of [[gallic acid]] groups and a pair of [[glucose]] molecules, all connected by a series of [[ester]] and [[glycosidic]] bonds.
-==Health Benefits==
+'''Punicalagin''' is a type of [[ellagitannin]], a class of [[polyphenol]]s found in certain [[plants]]. It is most notably present in [[pomegranate]]s (''Punica granatum''), from which it derives its name. Punicalagin is known for its potential [[antioxidant]] properties and is a subject of interest in [[nutritional science]] and [[pharmacology]].
-Punicalagin is known for its high [[antioxidant]] activity and is believed to be the primary component responsible for the antioxidant and health benefits associated with pomegranates. It has been shown to have anti-inflammatory, anti-viral, and anti-cancer properties in various research studies. It is also thought to have potential benefits for [[cardiovascular health]], including reducing [[LDL cholesterol]] levels and lowering blood pressure.
-==Food Sources==
+=== Chemical Structure ===
-The primary food source of punicalagin is the pomegranate. It is found in both the juice and the peel of the fruit, but is particularly concentrated in the peel. Other sources of punicalagin include certain types of nuts and berries, including [[walnuts]] and [[raspberries]].
-==See Also==
+Punicalagin is a large, water-soluble molecule that consists of a [[gallagic acid]] and [[ellagic acid]] moiety linked to a glucose core. It exists in two isomeric forms, alpha and beta, which differ in the orientation of the hydroxyl groups. The chemical formula for punicalagin is C<sub>48</sub>H<sub>28</sub>O<sub>30</sub>.
+=== Sources ===
+Punicalagin is primarily found in the [[peel]] and [[juice]] of pomegranates. It is also present in smaller amounts in other fruits such as [[walnuts]], [[chestnuts]], and certain types of [[berries]].
+=== Biological Activity ===
+Punicalagin is studied for its potential [[health benefits]], particularly its [[antioxidant]] and [[anti-inflammatory]] properties. It is believed to help in reducing [[oxidative stress]] and may have a role in [[cardiovascular health]].
+=== Metabolism ===
+Upon ingestion, punicalagin is hydrolyzed in the [[gut]] to release [[ellagic acid]], which is further metabolized by the [[microbiota]] to produce [[urolithins]]. These metabolites are thought to be responsible for the biological effects attributed to punicalagin.
+=== Potential Health Benefits ===
+Research suggests that punicalagin may have several health benefits, including:
+* '''Antioxidant Effects''': It helps in neutralizing [[free radicals]] and reducing oxidative damage to cells.
+* '''Anti-inflammatory Effects''': It may reduce inflammation by inhibiting the production of [[pro-inflammatory cytokines]].
+* '''Cardiovascular Health''': Punicalagin may improve [[blood pressure]] and [[cholesterol]] levels, contributing to heart health.
+== Related Pages ==
+* [[Ellagitannin]]
+* [[Pomegranate]]
+* [[Antioxidant]]
 * [[Polyphenol]]
-* [[Antioxidant]]
-* [[Pomegranate]]
-[[Category:Phytochemicals]]
+[[Category:Polyphenols]]
 [[Category:Antioxidants]]
-[[Category:Polyphenols]]
+[[Category:Ellagitannins]]
-{{Polyphenols}}
-{{Antioxidants}}
-{{food-stub}}