Sodium fumarate: Difference between revisions

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'''Sodium fumarate''' is the sodium salt of [[fumaric acid]], a key component in the [[Citric acid cycle|tricarboxylic acid cycle]]. It is a white, crystalline compound that is highly soluble in water and has a variety of uses in the food and pharmaceutical industries.
{{DISPLAYTITLE:Sodium fumarate}}


==Chemical Properties==
== Sodium Fumarate ==
Sodium fumarate is a white, crystalline powder with a molecular formula of C4H2Na2O4. It is highly soluble in water, and its solubility increases with temperature. It has a melting point of 287 degrees Celsius and decomposes upon heating.
[[File:Sodium_fumarate.png|thumb|right|Sodium fumarate structure]]
'''Sodium fumarate''' is the sodium salt of [[fumaric acid]], an important compound in the [[Krebs cycle]] (also known as the citric acid cycle), which is a key metabolic pathway that unifies carbohydrate, fat, and protein metabolism. Sodium fumarate is used in various biochemical applications and as a food additive.


==Production==
== Chemical Properties ==
Sodium fumarate can be produced by the neutralization of [[fumaric acid]] with [[sodium hydroxide]]. This reaction produces sodium fumarate and water. The resulting product is then purified and dried to obtain the final product.
Sodium fumarate is a white crystalline powder that is highly soluble in water. It is the sodium salt form of fumaric acid, which is a dicarboxylic acid. The chemical formula for sodium fumarate is C_H_NaO_.


==Uses==
== Biological Role ==
Sodium fumarate is used in a variety of industries due to its unique properties.  
In the [[Krebs cycle]], fumarate is formed by the oxidation of [[succinate]] by the enzyme [[succinate dehydrogenase]]. Fumarate is then hydrated to [[malate]] by the enzyme [[fumarase]]. This cycle is crucial for the production of [[adenosine triphosphate]] (ATP), which is the energy currency of the cell.


===Food Industry===
== Uses ==
In the food industry, sodium fumarate is used as a food additive. It acts as an acidity regulator, providing a sour taste and enhancing the flavor of foods. It is also used as a preservative due to its ability to inhibit the growth of certain types of bacteria.
Sodium fumarate is used in the food industry as an acidity regulator and as a flavoring agent. It is also used in the pharmaceutical industry for its potential therapeutic effects. In biochemistry, sodium fumarate is used in studies of the Krebs cycle and other metabolic pathways.


===Pharmaceutical Industry===
== Related Compounds ==
In the pharmaceutical industry, sodium fumarate is used as an excipient in the production of pharmaceutical products. It acts as a filler and binder in tablet formulations, improving the physical properties of the tablets.
* [[Fumaric acid]]
* [[Malic acid]]
* [[Succinic acid]]
* [[Citric acid]]


==Safety==
== Related Pages ==
Sodium fumarate is generally recognized as safe when used in accordance with good manufacturing practices. However, excessive consumption can lead to gastrointestinal discomfort, including nausea and diarrhea.
* [[Krebs cycle]]
 
* [[Metabolism]]
==See Also==
* [[Biochemistry]]
* [[Fumaric acid]]
* [[Sodium hydroxide]]
* [[Food additive]]
* [[Pharmaceutical industry]]


[[Category:Biochemistry]]
[[Category:Organic compounds]]
[[Category:Food additives]]
[[Category:Food additives]]
[[Category:Pharmaceutical ingredients]]
[[Category:Chemical compounds]]
{{Chem-stub}}
{{food-stub}}

Latest revision as of 11:09, 15 February 2025


Sodium Fumarate[edit]

Sodium fumarate structure

Sodium fumarate is the sodium salt of fumaric acid, an important compound in the Krebs cycle (also known as the citric acid cycle), which is a key metabolic pathway that unifies carbohydrate, fat, and protein metabolism. Sodium fumarate is used in various biochemical applications and as a food additive.

Chemical Properties[edit]

Sodium fumarate is a white crystalline powder that is highly soluble in water. It is the sodium salt form of fumaric acid, which is a dicarboxylic acid. The chemical formula for sodium fumarate is C_H_NaO_.

Biological Role[edit]

In the Krebs cycle, fumarate is formed by the oxidation of succinate by the enzyme succinate dehydrogenase. Fumarate is then hydrated to malate by the enzyme fumarase. This cycle is crucial for the production of adenosine triphosphate (ATP), which is the energy currency of the cell.

Uses[edit]

Sodium fumarate is used in the food industry as an acidity regulator and as a flavoring agent. It is also used in the pharmaceutical industry for its potential therapeutic effects. In biochemistry, sodium fumarate is used in studies of the Krebs cycle and other metabolic pathways.

Related Compounds[edit]

Related Pages[edit]