Kidney failure: Difference between revisions

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[[Kidney disease]] can get worse over time and may lead to kidney failure. If less than 15 percent of your kidney is working normally, that’s considered kidney failure. You may have symptoms from the buildup of waste products and extra water in your body.
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{{Infobox medical condition
[[File:Hemodialysismachine.jpg|Hemodialysismachine|thumb]]
| name            = Kidney failure
 
| image          = [[File:Hemodialysismachine.jpg|250px]]
| caption        = A [[hemodialysis]] machine, used to treat [[kidney failure]]
| synonyms        = [[Renal failure]], [[end-stage renal disease]] (ESRD)
| specialty      = [[Nephrology]]
| symptoms        = [[Decreased urine output]], [[swelling]], [[fatigue]], [[nausea]], [[shortness of breath]]
| complications  = [[Heart disease]], [[anemia]], [[bone disease]], [[hyperkalemia]]
| onset          = Gradual or sudden
| duration        = Long-term (chronic) or short-term (acute)
| causes          = [[Diabetes]], [[high blood pressure]], [[glomerulonephritis]], [[polycystic kidney disease]]
| risks          = [[Diabetes]], [[hypertension]], [[family history]], [[age]]
| diagnosis      = [[Blood tests]], [[urine tests]], [[imaging studies]], [[kidney biopsy]]
| treatment      = [[Dialysis]], [[kidney transplant]], [[medications]]
| prognosis      = Variable; depends on cause and treatment
| frequency      = Common, especially in older adults
}}
[[Kidney disease]] can get worse over time and may lead to kidney failure. If less than 15 percent of your kidney is working normally, that’s considered kidney failure. You may have symptoms from the buildup of waste products and extra water in your body.
== Other names ==
== Other names ==
Kidney failure, also called renal failure.
Kidney failure, also called renal failure.
==Types of kidney failure==  
==Types of kidney failure==  
Kidney failure can come on suddenly (acute kidney failure), or after years of kidney disease (chronic kidney failure). When your kidneys fail, [[dialysis]] or [[kidney transplant]] is necessary for survival.
Kidney failure can come on suddenly (acute kidney failure), or after years of kidney disease (chronic kidney failure). When your kidneys fail, [[dialysis]] or [[kidney transplant]] is necessary for survival.
==What is kidney failure?==
==What is kidney failure?==
A sudden drop in kidney function is called acute kidney failure. This develops quickly over a few hours or days, and mostly happens in people who are already critically ill.  
A sudden drop in kidney function is called acute kidney failure. This develops quickly over a few hours or days, and mostly happens in people who are already critically ill.  
==Chronic kidney disease and kidney failure==
==Chronic kidney disease and kidney failure==
More commonly, kidney failure happens as the final stage of chronic kidney disease. Called ‘end stage kidney disease,this is when about 90% of kidney function has been lost.
More commonly, kidney failure happens as the final stage of chronic kidney disease. Called ‘end stage kidney disease,’ this is when about 90% of kidney function has been lost.
 
==What causes kidney failure?==
==What causes kidney failure?==
Acute kidney failure most commonly affects people who are already hospitalised because they are very ill. It can be caused by:
Acute kidney failure most commonly affects people who are already hospitalised because they are very ill. It can be caused by:
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* damaged kidneys (for example, due to disease or toxins)
* damaged kidneys (for example, due to disease or toxins)
* blocked kidney drainage tubes (ureters) (for example, from kidney stones or tumours)
* blocked kidney drainage tubes (ureters) (for example, from kidney stones or tumours)
* Some medicines can also bring on acute kidney failure these include antibiotics, chemotherapy, imaging dyes, and medicines for blood pressure and osteoporosis.
* Some medicines can also bring on acute kidney failure — these include antibiotics, chemotherapy, imaging dyes, and medicines for blood pressure and osteoporosis.
 
The most common diseases causing chronic kidney failure are [[diabetes]], [[high blood pressure]] or inflammation in the kidney ([[glomerulonephritis]]).
The most common diseases causing chronic kidney failure are [[diabetes]], [[high blood pressure]] or inflammation in the kidney ([[glomerulonephritis]]).
==Signs and symptoms of kidney failure==
==Signs and symptoms of kidney failure==
Symptoms of acute kidney failure can include decreased amount of urine, fluid retention, confusion, nausea and chest pain. Symptoms of chronic kidney failure may include tiredness, weakness, nausea, vomiting, itching, restless legs, breathlessness, high blood pressure that can’t be controlled and night-time urination. If you notice any such symptoms, see your doctor.
Symptoms of acute kidney failure can include decreased amount of urine, fluid retention, confusion, nausea and chest pain. Symptoms of chronic kidney failure may include tiredness, weakness, nausea, vomiting, itching, restless legs, breathlessness, high blood pressure that can’t be controlled and night-time urination. If you notice any such symptoms, see your doctor.
 
==Kidney failure treatment==
==Kidney failure treatment==
There are three options for the treatment of kidney failure:
There are three options for the treatment of kidney failure:
* [[kidney transplant]], in which a diseased kidney is replaced by a healthy one from a donor
* [[kidney transplant]], in which a diseased kidney is replaced by a healthy one from a donor
* [[dialysis]], which uses a machine (haemodialysis) or other parts of the body (abdominal dialysis) to remove waste and extra fluid from your blood
* [[dialysis]], which uses a machine (haemodialysis) or other parts of the body (abdominal dialysis) to remove waste and extra fluid from your blood
* supportive care, which means providing all health care and support possible, but not attempting to cure the kidney failure. In this case the person with kidney failure will eventually die.
* supportive care, which means providing all health care and support possible, but not attempting to cure the kidney failure. In this case the person with kidney failure will eventually die.
==Preventing kidney failure==
==Preventing kidney failure==
You can help keep your kidneys as healthy as possible by maintaining a healthy weight, eating well, not smoking, keeping a check on your blood pressure, keeping within your glucose targets if you have diabetes, and exercising regularly.
You can help keep your kidneys as healthy as possible by maintaining a healthy weight, eating well, not smoking, keeping a check on your blood pressure, keeping within your glucose targets if you have diabetes, and exercising regularly.
* A haemodialysis uses a machine to remove waste and extra fluid from your blood.
* A haemodialysis uses a machine to remove waste and extra fluid from your blood.
* Illustration showing how a peritoneal dialysis works.
* Illustration showing how a peritoneal dialysis works.
* A dialysis using the abdomen to remove waste and extra fluid from your body.
* A dialysis using the abdomen to remove waste and extra fluid from your body.
If you have chronic kidney disease, medical treatments and lifestyle changes can delay or prevent its progression to kidney failure, and also help control symptoms.
If you have chronic kidney disease, medical treatments and lifestyle changes can delay or prevent its progression to kidney failure, and also help control symptoms.
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Latest revision as of 01:39, 8 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
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Kidney failure
Synonyms Renal failure, end-stage renal disease (ESRD)
Pronounce N/A
Specialty Nephrology
Symptoms Decreased urine output, swelling, fatigue, nausea, shortness of breath
Complications Heart disease, anemia, bone disease, hyperkalemia
Onset Gradual or sudden
Duration Long-term (chronic) or short-term (acute)
Types N/A
Causes Diabetes, high blood pressure, glomerulonephritis, polycystic kidney disease
Risks Diabetes, hypertension, family history, age
Diagnosis Blood tests, urine tests, imaging studies, kidney biopsy
Differential diagnosis N/A
Prevention N/A
Treatment Dialysis, kidney transplant, medications
Medication N/A
Prognosis Variable; depends on cause and treatment
Frequency Common, especially in older adults
Deaths N/A


Kidney disease can get worse over time and may lead to kidney failure. If less than 15 percent of your kidney is working normally, that’s considered kidney failure. You may have symptoms from the buildup of waste products and extra water in your body.

Other names[edit]

Kidney failure, also called renal failure.

Types of kidney failure[edit]

Kidney failure can come on suddenly (acute kidney failure), or after years of kidney disease (chronic kidney failure). When your kidneys fail, dialysis or kidney transplant is necessary for survival.

What is kidney failure?[edit]

A sudden drop in kidney function is called acute kidney failure. This develops quickly over a few hours or days, and mostly happens in people who are already critically ill.

Chronic kidney disease and kidney failure[edit]

More commonly, kidney failure happens as the final stage of chronic kidney disease. Called ‘end stage kidney disease,’ this is when about 90% of kidney function has been lost.

What causes kidney failure?[edit]

Acute kidney failure most commonly affects people who are already hospitalised because they are very ill. It can be caused by:

  • slow blood flow to the kidneys (for example, due to an accident, burns or dehydration)
  • damaged kidneys (for example, due to disease or toxins)
  • blocked kidney drainage tubes (ureters) (for example, from kidney stones or tumours)
  • Some medicines can also bring on acute kidney failure ‚Äî these include antibiotics, chemotherapy, imaging dyes, and medicines for blood pressure and osteoporosis.

The most common diseases causing chronic kidney failure are diabetes, high blood pressure or inflammation in the kidney (glomerulonephritis).

Signs and symptoms of kidney failure[edit]

Symptoms of acute kidney failure can include decreased amount of urine, fluid retention, confusion, nausea and chest pain. Symptoms of chronic kidney failure may include tiredness, weakness, nausea, vomiting, itching, restless legs, breathlessness, high blood pressure that can’t be controlled and night-time urination. If you notice any such symptoms, see your doctor.

Kidney failure treatment[edit]

There are three options for the treatment of kidney failure:

  • kidney transplant, in which a diseased kidney is replaced by a healthy one from a donor
  • dialysis, which uses a machine (haemodialysis) or other parts of the body (abdominal dialysis) to remove waste and extra fluid from your blood
  • supportive care, which means providing all health care and support possible, but not attempting to cure the kidney failure. In this case the person with kidney failure will eventually die.

Preventing kidney failure[edit]

You can help keep your kidneys as healthy as possible by maintaining a healthy weight, eating well, not smoking, keeping a check on your blood pressure, keeping within your glucose targets if you have diabetes, and exercising regularly.

  • A haemodialysis uses a machine to remove waste and extra fluid from your blood.
  • Illustration showing how a peritoneal dialysis works.
  • A dialysis using the abdomen to remove waste and extra fluid from your body.

If you have chronic kidney disease, medical treatments and lifestyle changes can delay or prevent its progression to kidney failure, and also help control symptoms.

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PubMed
Wikipedia
Health science - Medicine - Nephrology - edit
Diseases of the glomerulus
Lupus nephritis | Post-infectious glomerulonephritis | Minimal change disease | Focal segmental glomerulosclerosis | Diabetic nephropathy
Diseases of the proximal convoluted tubules
Fanconi syndrome (Type II renal tubular acidosis) | renal cell carcinoma
Diseases of the distal convoluted tubules
pseudohypoaldosteronism (Type IV renal tubular acidosis)
Diseases of the collecting duct
Type I renal tubular acidosis
Tumours of the kidney
renal cell carcinoma | Wilms' tumour (children)
Diseases of the renal vasculature
renal artery stenosis | vasculitis | atheroembolic disease
Tubulointerstitial diseases of the kidney
Drug-induced interstitial nephritis | Obstructive nephropathy | Radiation nephritis | Reflux nephropathy | Sarcoidosis
Genetic diseases of the kidney/syndromes associated with kidney dysfunction
Alport syndrome | Polycystic kidney disease | Wilms' tumour (children)

von Hippel-Lindau syndrome | Hereditary papillary renal carcinoma | Birt-Hogg-Dube syndrome | Hereditary renal carcinoma

Chronic kidney disease and related conditions

Chronic Kidney Disease

Anemia in CKD | Causes of CKD | CKD Overview | CKD Tests and Diagnosis | Diabetic Kidney Disease | Eating Right for CKD | High Blood Pressure and Kidney Disease | Managing CKD | Mineral and Bone Disorder in CKD | Nutrition for Advanced CKD in Adults | Preventing CKD | Quick Reference on UACR & GFR

Kidney Failure

Eating and Nutrition for Hemodialysis | Financial Help for Treatment of Kidney Failure | Hemodialysis | Kidney Failure | Kidney Transplant | Peritoneal Dialysis

Other Kidney Topics

Acquired Cystic Kidney Disease | Amyloidosis and Kidney Disease | Diabetes Insipidus | Ectopic Kidney | Glomerular Diseases | Goodpasture Syndrome | Henoch-Schönlein Purpura | IgA Nephropathy | Kidney Dysplasia | Kidney Infection (Pyelonephritis) | Kidney Stones | Lupus Nephritis | Medullary Sponge Kidney | Nephrotic Syndrome in Adults | Pain Medicine and Kidney Damage | Polycystic Kidney Disease (PKD) | Renal Artery Stenosis | Renal Tubular Acidosis | Simple Kidney Cysts | Solitary Kidney | Your Kidneys and How They Work | Your Urinary Tract and How It Works