Thecoma

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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W8MD medical weight loss NYC and sleep center NYC

Thecoma
Micrograph of a thecoma.
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Abdominal pain, abdominal distension, menstrual irregularities
Complications	Ascites, Meigs' syndrome
Onset	Typically in postmenopausal women
Duration	Variable
Types	Luteinized thecoma, non-luteinized thecoma
Causes	Unknown
Risks	Postmenopausal status
Diagnosis	Pelvic ultrasound, CT scan, MRI, histopathology
Differential diagnosis	Fibroma, granulosa cell tumor, Sertoli-Leydig cell tumor
Prevention	N/A
Treatment	Surgical excision
Medication	None specific
Prognosis	Generally good with treatment
Frequency	Rare
Deaths	N/A

Thecoma is a type of ovarian tumor that is part of the group of tumors known as sex cord-stromal tumors. These tumors are derived from the sex cords of the developing gonad and the stroma, or connective tissue, of the ovary. Thecomas are typically benign, meaning they are not cancerous, and they are most commonly found in postmenopausal women.

Symptoms

The symptoms of a thecoma can vary depending on the size and location of the tumor. Some women may not have any symptoms at all, while others may experience abdominal pain, bloating, or a feeling of fullness. In some cases, thecomas can produce estrogen, which can lead to symptoms such as vaginal bleeding, menstrual irregularities, or signs of endometrial hyperplasia or endometrial cancer.

Diagnosis

The diagnosis of a thecoma is typically made through a combination of physical examination, imaging studies, and biopsy. Imaging studies such as ultrasound, CT scan, or MRI can help to identify the presence and location of the tumor. A biopsy, in which a sample of the tumor is removed for examination under a microscope, can confirm the diagnosis.

Treatment

The treatment for a thecoma will depend on the size and location of the tumor, as well as the patient's overall health and preferences. Treatment options may include surgery, hormone therapy, or observation. Surgery is typically the first-line treatment and may involve removal of the tumor or, in some cases, removal of the entire ovary. Hormone therapy may be used in cases where the tumor is producing estrogen.

Prognosis

The prognosis for women with a thecoma is generally good, as these tumors are typically benign and slow-growing. However, in rare cases, thecomas can become malignant, or cancerous. Regular follow-up with a healthcare provider is important to monitor for any changes or signs of malignancy.

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