Stroma

Stroma is a term used in biology to refer to the supportive framework of a biological cell, tissue, or organ. It is contrasted with the parenchyma, which refers to the functional parts of an organ in the body.

Overview

The stroma of a tissue or organ usually includes the connective tissues that provide structural support. It may also include blood vessels, nerves, and other structures. The stroma is an important component of many organs, including the kidney, liver, and lung. In the eye, the stroma refers to the connective tissue of the cornea.

Function

The stroma provides structural support to the cells and tissues within an organ. It also plays a role in the function of the organ. For example, in the kidney, the stroma helps to filter waste products from the blood. In the lung, the stroma helps to support the air sacs that are responsible for gas exchange.

In disease

Changes in the stroma can contribute to disease. For example, in cancer, changes in the stroma can promote tumor growth and spread. Research is ongoing to understand the role of the stroma in disease and to develop treatments that target the stroma.

See also

• Extracellular matrix
• Connective tissue
• Parenchyma