Loeffler endocarditis: Difference between revisions

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{{Infobox medical condition
| name            = Loeffler endocarditis
| synonyms        = [[Endomyocardial fibrosis]], [[Hypereosinophilic syndrome]]
| specialty      = [[Cardiology]]
| symptoms        = [[Fatigue]], [[shortness of breath]], [[chest pain]], [[heart failure]]
| complications  = [[Heart failure]], [[thromboembolism]], [[arrhythmias]]
| onset          = Typically in [[adulthood]]
| duration        = Chronic
| causes          = [[Hypereosinophilia]]
| risks          = [[Parasitic infections]], [[autoimmune diseases]], [[allergic reactions]]
| diagnosis      = [[Echocardiogram]], [[MRI]], [[endomyocardial biopsy]]
| differential    = [[Restrictive cardiomyopathy]], [[constrictive pericarditis]]
| treatment      = [[Corticosteroids]], [[cytotoxic drugs]], [[anticoagulation]], [[surgery]]
| prognosis      = Variable, depends on severity and response to treatment
| frequency      = Rare
}}
'''Loeffler endocarditis''' is a rare form of [[heart disease]] characterized by a thickening of the [[endocardium]] due to an increase in [[eosinophils]], a type of white blood cell. This condition is part of a broader category of diseases known as [[eosinophilic heart diseases]].
'''Loeffler endocarditis''' is a rare form of [[heart disease]] characterized by a thickening of the [[endocardium]] due to an increase in [[eosinophils]], a type of white blood cell. This condition is part of a broader category of diseases known as [[eosinophilic heart diseases]].
== Symptoms ==
== Symptoms ==
The symptoms of Loeffler endocarditis can vary greatly from person to person. Common symptoms include [[fatigue]], [[shortness of breath]], [[chest pain]], and [[edema]] (swelling) in the legs and feet. In severe cases, the disease can lead to [[heart failure]].
The symptoms of Loeffler endocarditis can vary greatly from person to person. Common symptoms include [[fatigue]], [[shortness of breath]], [[chest pain]], and [[edema]] (swelling) in the legs and feet. In severe cases, the disease can lead to [[heart failure]].
== Causes ==
== Causes ==
The exact cause of Loeffler endocarditis is unknown. However, it is often associated with conditions that cause an increase in eosinophils, such as [[parasitic infections]], [[allergies]], and certain types of [[cancer]].
The exact cause of Loeffler endocarditis is unknown. However, it is often associated with conditions that cause an increase in eosinophils, such as [[parasitic infections]], [[allergies]], and certain types of [[cancer]].
== Diagnosis ==
== Diagnosis ==
Diagnosis of Loeffler endocarditis typically involves a combination of [[medical history]], physical examination, and diagnostic tests. These tests may include [[blood tests]], [[echocardiogram]], and [[cardiac MRI]].
Diagnosis of Loeffler endocarditis typically involves a combination of [[medical history]], physical examination, and diagnostic tests. These tests may include [[blood tests]], [[echocardiogram]], and [[cardiac MRI]].
== Treatment ==
== Treatment ==
Treatment for Loeffler endocarditis is primarily aimed at reducing the number of eosinophils and managing the symptoms. This may involve medications such as [[corticosteroids]], [[diuretics]], and [[heart medications]]. In severe cases, surgery may be required to remove the thickened endocardium.
Treatment for Loeffler endocarditis is primarily aimed at reducing the number of eosinophils and managing the symptoms. This may involve medications such as [[corticosteroids]], [[diuretics]], and [[heart medications]]. In severe cases, surgery may be required to remove the thickened endocardium.
== Prognosis ==
== Prognosis ==
The prognosis for Loeffler endocarditis can vary depending on the severity of the disease and the individual's overall health. With early diagnosis and appropriate treatment, many people with this condition can lead a normal life.
The prognosis for Loeffler endocarditis can vary depending on the severity of the disease and the individual's overall health. With early diagnosis and appropriate treatment, many people with this condition can lead a normal life.
== See also ==
== See also ==
* [[Eosinophilic heart diseases]]
* [[Eosinophilic heart diseases]]
* [[Endocarditis]]
* [[Endocarditis]]
* [[Heart disease]]
* [[Heart disease]]
[[Category:Cardiology]]
[[Category:Cardiology]]
[[Category:Rare diseases]]
[[Category:Rare diseases]]
[[Category:Heart diseases]]
[[Category:Heart diseases]]
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Latest revision as of 00:54, 4 April 2025


Loeffler endocarditis
Synonyms Endomyocardial fibrosis, Hypereosinophilic syndrome
Pronounce N/A
Specialty Cardiology
Symptoms Fatigue, shortness of breath, chest pain, heart failure
Complications Heart failure, thromboembolism, arrhythmias
Onset Typically in adulthood
Duration Chronic
Types N/A
Causes Hypereosinophilia
Risks Parasitic infections, autoimmune diseases, allergic reactions
Diagnosis Echocardiogram, MRI, endomyocardial biopsy
Differential diagnosis Restrictive cardiomyopathy, constrictive pericarditis
Prevention N/A
Treatment Corticosteroids, cytotoxic drugs, anticoagulation, surgery
Medication N/A
Prognosis Variable, depends on severity and response to treatment
Frequency Rare
Deaths N/A


Loeffler endocarditis is a rare form of heart disease characterized by a thickening of the endocardium due to an increase in eosinophils, a type of white blood cell. This condition is part of a broader category of diseases known as eosinophilic heart diseases.

Symptoms[edit]

The symptoms of Loeffler endocarditis can vary greatly from person to person. Common symptoms include fatigue, shortness of breath, chest pain, and edema (swelling) in the legs and feet. In severe cases, the disease can lead to heart failure.

Causes[edit]

The exact cause of Loeffler endocarditis is unknown. However, it is often associated with conditions that cause an increase in eosinophils, such as parasitic infections, allergies, and certain types of cancer.

Diagnosis[edit]

Diagnosis of Loeffler endocarditis typically involves a combination of medical history, physical examination, and diagnostic tests. These tests may include blood tests, echocardiogram, and cardiac MRI.

Treatment[edit]

Treatment for Loeffler endocarditis is primarily aimed at reducing the number of eosinophils and managing the symptoms. This may involve medications such as corticosteroids, diuretics, and heart medications. In severe cases, surgery may be required to remove the thickened endocardium.

Prognosis[edit]

The prognosis for Loeffler endocarditis can vary depending on the severity of the disease and the individual's overall health. With early diagnosis and appropriate treatment, many people with this condition can lead a normal life.

See also[edit]

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