Large granular lymphocytic leukemia: Difference between revisions

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{{Infobox medical condition
| name            = Large granular lymphocytic leukemia
| synonyms        = LGL leukemia
| field          = [[Hematology]]
| symptoms        = [[Fatigue (medical)|Fatigue]], [[neutropenia]], [[anemia]], [[splenomegaly]], [[rheumatoid arthritis]]
| complications  = [[Infections]], [[autoimmune disorders]]
| onset          = Typically in adults
| duration        = Chronic
| causes          = Unknown, possibly [[autoimmune]]
| risks          = [[Rheumatoid arthritis]], [[autoimmune disorders]]
| diagnosis      = [[Blood test]], [[bone marrow biopsy]], [[flow cytometry]]
| differential    = [[Chronic lymphocytic leukemia]], [[T-cell prolymphocytic leukemia]], [[Felty's syndrome]]
| treatment      = [[Immunosuppressive therapy]], [[chemotherapy]], [[cyclosporine]], [[methotrexate]]
| prognosis      = Variable, often indolent
| frequency      = Rare
}}
Large granular lymphocytic leukemia (LGL) is a type of leukemia that affects a specific type of white blood cell called lymphocytes. It is a slow-growing form of leukemia and symptoms may not appear for years. Treatment options include observation, immunosuppressive therapy, or chemotherapy.
Large granular lymphocytic leukemia (LGL) is a type of leukemia that affects a specific type of white blood cell called lymphocytes. It is a slow-growing form of leukemia and symptoms may not appear for years. Treatment options include observation, immunosuppressive therapy, or chemotherapy.
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Latest revision as of 02:50, 4 April 2025


Large granular lymphocytic leukemia
Synonyms LGL leukemia
Pronounce N/A
Specialty N/A
Symptoms Fatigue, neutropenia, anemia, splenomegaly, rheumatoid arthritis
Complications Infections, autoimmune disorders
Onset Typically in adults
Duration Chronic
Types N/A
Causes Unknown, possibly autoimmune
Risks Rheumatoid arthritis, autoimmune disorders
Diagnosis Blood test, bone marrow biopsy, flow cytometry
Differential diagnosis Chronic lymphocytic leukemia, T-cell prolymphocytic leukemia, Felty's syndrome
Prevention N/A
Treatment Immunosuppressive therapy, chemotherapy, cyclosporine, methotrexate
Medication N/A
Prognosis Variable, often indolent
Frequency Rare
Deaths N/A


Large granular lymphocytic leukemia (LGL) is a type of leukemia that affects a specific type of white blood cell called lymphocytes. It is a slow-growing form of leukemia and symptoms may not appear for years. Treatment options include observation, immunosuppressive therapy, or chemotherapy.

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