Uterine adenosarcoma

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Uterine adenosarcoma
Micrograph of uterine adenosarcoma
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Abnormal uterine bleeding, Pelvic pain, Pelvic mass
Complications Metastasis, Recurrence
Onset Typically in postmenopausal women
Duration Variable
Types Low-grade, High-grade
Causes Unknown
Risks Tamoxifen use, Radiation therapy
Diagnosis Histopathology, Imaging studies
Differential diagnosis Endometrial carcinoma, Uterine sarcoma, Endometrial polyp
Prevention Regular gynecological examination
Treatment Surgery, Radiation therapy, Chemotherapy
Medication Hormonal therapy
Prognosis Generally good with early detection
Frequency Rare
Deaths N/A


Uterine adenosarcoma is a rare type of cancer that affects the uterus. It is characterized by the presence of both malignant and benign components within the tumor. The malignant component consists of stromal cells that have the potential to spread to other parts of the body, while the benign component consists of glandular cells that do not have the ability to metastasize.

Symptoms

Symptoms of uterine adenosarcoma may include abnormal vaginal bleeding, pelvic pain, and a feeling of fullness in the lower abdomen. Some women may also experience pain during intercourse or have a mass or lump in the pelvic area.

Diagnosis

Diagnosis of uterine adenosarcoma typically involves a combination of imaging tests, such as ultrasound and MRI, as well as a biopsy of the tumor to confirm the presence of both malignant and benign components.

Treatment

Treatment for uterine adenosarcoma usually involves surgery to remove the tumor and surrounding tissue. In some cases, radiation therapy or chemotherapy may be recommended to help prevent the cancer from recurring.

Prognosis

The prognosis for uterine adenosarcoma depends on various factors, including the stage of the cancer at the time of diagnosis and the presence of any underlying health conditions. Early detection and treatment can improve the chances of successful outcomes.

Epidemiology

Uterine adenosarcoma is a rare type of cancer, accounting for less than 5% of all uterine malignancies. It most commonly affects women in their 40s and 50s, although it can occur at any age.

References


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Contributors: Prab R. Tumpati, MD