Urticaria pigmentosa

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Urticaria Pigmentosa

Urticaria Pigmentosa (pronounced: ur-ti-kar-ee-uh pig-men-toh-suh), also known as UP, is a form of cutaneous mastocytosis characterized by brownish or reddish patches on the skin.

Etymology

The term 'Urticaria Pigmentosa' is derived from the Latin word 'urtica', meaning 'nettle', and the Latin word 'pigmentosa', meaning 'colored'. This refers to the nettle-like rash and the pigmented nature of the skin lesions associated with this condition.

Definition

Urticaria Pigmentosa is a rare skin disorder that is characterized by the presence of excessive mast cells in the skin. These cells release chemicals such as histamine that cause itching, redness, and other symptoms. The condition is usually diagnosed in infancy or early childhood, but it can also occur in adults.

Symptoms

The main symptom of Urticaria Pigmentosa is the presence of small, brownish or reddish patches on the skin. These patches can become raised and itchy, especially when rubbed. Other symptoms can include flushing, abdominal pain, diarrhea, and in severe cases, anaphylaxis.

Diagnosis

Diagnosis of Urticaria Pigmentosa is usually based on the characteristic skin lesions. A skin biopsy may be performed to confirm the diagnosis. In this procedure, a small sample of skin is removed and examined under a microscope to look for an increased number of mast cells.

Treatment

Treatment for Urticaria Pigmentosa is aimed at managing the symptoms. This can include avoiding triggers that cause the mast cells to release their chemicals, such as certain foods, medications, and physical stimuli. Medications such as antihistamines and corticosteroids may also be used to help control symptoms.

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