Tumorigenesis
Tumorigenesis
Tumorigenesis (pronounced: too-mor-i-gen-e-sis) is a complex, multi-step process that involves the transformation of normal cells into cancer cells. The term is derived from the Latin word 'tumor' meaning swelling, and the Greek word 'genesis' meaning origin or source.
Etymology
The term 'Tumorigenesis' is a combination of two words: 'Tumor' and 'Genesis'. 'Tumor' is derived from the Latin word 'tumere' which means to swell, and 'Genesis' is derived from the Greek word 'geneseos' which means origin or source. Thus, 'Tumorigenesis' refers to the origin or source of a swelling or growth, specifically referring to the formation of a tumor.
Process
Tumorigenesis involves a series of changes at the cellular and genetic level that ultimately lead to the development of a tumor. This process is typically initiated by a genetic mutation or an environmental factor that causes a cell to divide and grow in an uncontrolled manner. Over time, these abnormal cells can accumulate additional mutations, leading to the development of a tumor. This process is influenced by a variety of factors, including the individual's genetic makeup, environmental exposures, and lifestyle factors.
Related Terms
- Oncogene: A gene that has the potential to cause cancer. In tumor cells, these genes are often mutated or expressed at high levels.
- Carcinogenesis: The process of initiating and promoting cancer. It is often used interchangeably with tumorigenesis.
- Neoplasm: An abnormal growth of tissue, which can be benign (non-cancerous) or malignant (cancerous).
- Metastasis: The process by which cancer cells spread from the place where they first formed to another part of the body.
- Apoptosis: A form of programmed cell death that occurs in multicellular organisms. It is a crucial component in maintaining the health of the body by eliminating old cells, unnecessary cells, and unhealthy cells.
External links
- Medical encyclopedia article on Tumorigenesis
- Wikipedia's article - Tumorigenesis
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