Thromboxane
Thromboxane
Thromboxane (pronounced: throm-box-ane) is a type of eicosanoid that is produced in platelets during the process of blood clotting. It is a member of the prostanoid class of fatty acids and is known for its role in promoting platelet aggregation and arterial constriction.
Etymology
The term "Thromboxane" is derived from its role in thrombosis (the formation of blood clots) and its structural relationship to the prostaglandins, which are also part of the eicosanoid family. The suffix "-ane" is used to denote its cyclic nature.
Function
Thromboxane is produced by platelets during blood clotting. It promotes vasoconstriction and platelet aggregation, which are crucial steps in the clotting process. Thromboxane is synthesized from arachidonic acid via the cyclooxygenase pathway.
Related Terms
- Eicosanoid: A group of compounds that includes thromboxane, prostaglandins, and leukotrienes. They are derived from arachidonic acid and have various roles in inflammation, immunity, and other physiological processes.
- Platelet: A type of blood cell that plays a key role in blood clotting. Platelets produce thromboxane when they are activated during the clotting process.
- Vasoconstriction: The narrowing of blood vessels, which increases blood pressure. Thromboxane promotes vasoconstriction as part of its role in blood clotting.
- Arachidonic acid: A type of fatty acid that is the precursor to eicosanoids, including thromboxane.
- Cyclooxygenase: An enzyme that catalyzes the conversion of arachidonic acid to prostaglandins and thromboxane.
External links
- Medical encyclopedia article on Thromboxane
- Wikipedia's article - Thromboxane
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