Tannerella forsythia

Tannerella forsythia (/tænəˈrɛlə fɔːrˈsaɪθiə/) is a species of Gram-negative bacteria in the Bacteroidetes phylum. It is an anaerobic, non-motile bacterium that is part of the human oral microbiota, and is associated with periodontal diseases, including gingivitis and periodontitis.

Etymology

The bacterium is named after Anne Tanner and Sigmund Socransky, who first isolated it, and the Greek word "forsythia", which means "hidden", referring to the bacterium's elusive nature and difficulty to culture.

Characteristics

Tannerella forsythia is a rod-shaped bacterium that is difficult to culture due to its complex nutritional requirements. It is often found in the subgingival plaque, where it forms a complex with other bacteria, such as Porphyromonas gingivalis and Treponema denticola, known as the "red complex".

Pathogenicity

Tannerella forsythia is associated with various forms of periodontal diseases. It produces a variety of virulence factors, including proteases and other enzymes, that contribute to tissue destruction and inflammation in the periodontium.

Treatment

Treatment of infections caused by Tannerella forsythia typically involves mechanical debridement of the periodontal pockets, combined with systemic or local administration of antibiotics.

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Tannerella forsythia