TDMA (drug)
Overview of the drug TDMA
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TDMA (1-(2,5-dimethoxy-4-methylphenyl)propan-2-amine) is a psychedelic phenethylamine of the amphetamine class. It is known for its psychoactive effects and is structurally related to other compounds such as DOM and TMA-2.
Chemical Structure
TDMA is a derivative of the phenethylamine class, characterized by a phenyl ring bound to an amino group through a two-carbon side chain. The chemical structure of TDMA includes two methoxy groups at the 2 and 5 positions and a methyl group at the 4 position of the phenyl ring, with an additional methyl group on the alpha carbon of the side chain, making it an amphetamine.
Pharmacology
TDMA acts primarily as a serotonin receptor agonist, similar to other psychedelic amphetamines. It is believed to exert its effects by binding to the 5-HT2A receptor, which is a common target for psychedelic substances. The activation of this receptor is associated with altered perception, mood, and cognition.
Effects
The effects of TDMA are similar to those of other psychedelic amphetamines, including altered sensory perception, changes in mood, and cognitive shifts. Users may experience visual and auditory hallucinations, a sense of euphoria, and altered time perception. The intensity and duration of these effects can vary based on dosage and individual sensitivity.
Synthesis
TDMA can be synthesized from 2,5-dimethoxy-4-methylbenzaldehyde through a series of chemical reactions. The synthesis involves the formation of the corresponding nitrostyrene, followed by reduction to the amine. This process is similar to the synthesis of other phenethylamine derivatives.
Legal Status
The legal status of TDMA varies by country. In some jurisdictions, it may be classified as a controlled substance due to its structural similarity to other regulated psychedelic compounds. It is important for researchers and users to be aware of the legal implications of possessing or using TDMA in their respective regions.
Related Compounds
TDMA is part of a broader class of psychedelic amphetamines, which includes:
These compounds share similar mechanisms of action and effects, although they differ in potency and duration.
See Also
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Contributors: Prab R. Tumpati, MD