Spanish National Cancer Research Centre
Research institute in Spain
The Spanish National Cancer Research Centre (Spanish: Centro Nacional de Investigaciones Oncológicas
, CNIO) is a leading biomedical research institute located in Madrid, Spain. It is dedicated to the study of cancer and the development of new therapeutic strategies to combat this disease. The CNIO is renowned for its cutting-edge research and its contribution to the global understanding of cancer biology.
History[edit]
The CNIO was established in 1998 by the Spanish Ministry of Health with the aim of fostering cancer research in Spain. Since its inception, the CNIO has grown to become one of the most prominent cancer research centers in Europe, attracting top scientists from around the world.
Research Programs[edit]
The CNIO is organized into several research programs, each focusing on different aspects of cancer research:
Molecular Oncology[edit]
The Molecular Oncology program investigates the genetic and molecular mechanisms that drive cancer development and progression. Researchers in this program study oncogenes, tumor suppressor genes, and the signaling pathways involved in cancer.
Structural Biology and Biocomputing[edit]
This program focuses on understanding the three-dimensional structures of proteins and other macromolecules involved in cancer. By using X-ray crystallography, NMR spectroscopy, and computational biology, scientists aim to uncover the molecular basis of cancer and identify potential drug targets.
Experimental Therapeutics[edit]
The Experimental Therapeutics program is dedicated to the discovery and development of new cancer treatments. Researchers work on drug discovery, preclinical studies, and the translation of laboratory findings into clinical applications.
Human Cancer Genetics[edit]
This program studies the genetic basis of cancer susceptibility and the role of inherited genetic mutations in cancer risk. Researchers conduct genome-wide association studies and investigate familial cancer syndromes.
Clinical Research[edit]
The Clinical Research program bridges the gap between laboratory research and patient care. It involves clinical trials, biomarker discovery, and the development of personalized medicine approaches for cancer treatment.
Facilities[edit]
The CNIO is equipped with state-of-the-art facilities that support its research activities. These include advanced laboratories, core facilities for genomics, proteomics, and bioinformatics, as well as animal research facilities.

Collaborations[edit]
The CNIO collaborates with numerous national and international research institutions, universities, and hospitals. These collaborations enhance the center's research capabilities and facilitate the exchange of knowledge and resources.
Education and Training[edit]
The CNIO is committed to training the next generation of cancer researchers. It offers various educational programs, including PhD and postdoctoral training, as well as workshops and seminars for scientists at all career stages.
Related pages[edit]
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