Sinus node dysfunction

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Sinus node dysfunction
ECG showing sinus pause
Synonyms Sick sinus syndrome, sinus node disease
Pronounce N/A
Specialty N/A
Symptoms Bradycardia, fatigue, dizziness, syncope
Complications Heart failure, stroke
Onset Typically in older adults
Duration Chronic
Types N/A
Causes Fibrosis of the sinoatrial node, ischemic heart disease, medications
Risks Age, hypertension, diabetes mellitus
Diagnosis Electrocardiogram (ECG), Holter monitor
Differential diagnosis Atrioventricular block, atrial fibrillation
Prevention N/A
Treatment Pacemaker implantation, medication adjustment
Medication N/A
Prognosis Variable, depends on underlying cause and treatment
Frequency Common in older adults
Deaths N/A


Brady-tachy syndrome with AV junctional rhythm
Brady-tachy syndrome with atrial fibrillation
Sinus bradycardia at 49 bpm

Sinus node dysfunction (SND), also known as sick sinus syndrome (SSS), is a group of heart rhythm problems (arrhythmias) in which the heart's natural pacemaker (sinus node) doesn't work properly. The sinus node is an area of specialized cells in the upper right chamber of the heart that controls the rhythm of your heart. Normally, the sinus node produces a steady pace of regular electrical impulses. In sick sinus syndrome, these signals are abnormally paced. A person with sinus node dysfunction may have heart rhythms that are too fast, too slow, punctuated by long pauses — or an alternating combination of all of these rhythm problems. Sinus node dysfunction is relatively uncommon, but the risk of developing it increases with age. Many people with sinus node dysfunction eventually need a pacemaker to keep the heart in a regular rhythm.

Symptoms[edit]

Sinus node dysfunction often doesn't cause noticeable symptoms. When symptoms do occur, they may mimic those caused by other health problems, making the condition difficult to diagnose. Symptoms may include:

Causes[edit]

Sinus node dysfunction is associated with damage to or degeneration of the sinus node — often the result of underlying conditions or medical treatments. Conditions that can cause or contribute to problems with the sinus node include:

Treatment[edit]

Treatment for sinus node dysfunction usually involves addressing underlying health problems and reducing symptoms. If symptoms are severe or the condition is causing more serious heart rhythm problems, treatment may involve medications to control the heart rate or the implantation of a pacemaker.

See also[edit]

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