Seminiferous tubule

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Biology of the vertebrates - a comparative study of man and his animal allies (1949) (20195953650)

 

Illu testis schematic
Seminiferous tubule

 

seminiferous tubule and sperm low mag

The Seminiferous Tubules are a component of the male reproductive system that are located within the testes. They are the site of the germination, maturation, and transportation of the sperm cells within the male body. The epithelium of the tubule consists of a type of sustentacular cells known as Sertoli cells, which are a crucial part of spermatogenesis.

Structure

The seminiferous tubules are a coiled network of tubes that measure up to half a mile in length in each testis. They are lined with a layer of cells that progress through the stages of spermatogenesis to produce sperm. The tubules are surrounded by myoid cells that contract rhythmically to move the immature sperm towards the rete testis for further maturation.

Function

The primary function of the seminiferous tubules is the production of sperm. This process, known as spermatogenesis, involves the development of spermatogonia into mature spermatozoa. The process is facilitated by Sertoli cells, which provide nourishment and structural support for the developing sperm cells.

Clinical significance

Damage or disease affecting the seminiferous tubules can lead to infertility in males. Conditions such as varicocele, cryptorchidism, and certain genetic disorders can affect the function of the tubules and result in a reduced sperm count or poor sperm quality.

  • Seminiferous tubule (right) with sperm (black, tiny, ovoid). H&E stain.

  • Longitudinal section through the left side of the scrotum and the left testis (seminiferous tubules visible in center, but not labeled).

  • Rattestis.jpg

    Photomicrograph of section through rat testis, showing seminiferous tubules.

See also

Male reproductive system
Internal
External
Penis
Scrotum


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Contributors: Prab R. Tumpati, MD