Rolipram

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Rolipram

Rolipram (pronunciation: roh-LIP-ram) is a selective PDE4 inhibitor that has been used in research for its potential anti-inflammatory effects.

Etymology

The term "Rolipram" is derived from the chemical name RO-20-1724 LIpid Phosphodiesterase inhibitor RAM.

Pharmacology

Rolipram works by inhibiting the action of PDE4, an enzyme that breaks down cyclic adenosine monophosphate (cAMP) in the body. By preventing the breakdown of cAMP, Rolipram can increase the levels of this important signaling molecule in cells, which can have a variety of effects, including reducing inflammation.

Clinical Use

While Rolipram has been studied for its potential use in a variety of conditions, including depression, Schizophrenia, and COPD, it is not currently approved for use in any indication.

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