Renal clearance
Renal Clearance
Renal clearance (pronunciation: /ˈriːnəl ˈklɪərəns/) is a measure of the efficiency of the kidneys in removing (clearing) a substance from the blood. It is a concept in nephrology and is often used in the assessment of renal function.
Etymology
The term "renal" is derived from the Latin word "renes", meaning kidneys. "Clearance" comes from the Old French "clerer", meaning to clear.
Definition
Renal clearance is defined as the volume of plasma from which a substance is completely removed by the kidneys per unit time. It is usually measured in milliliters per minute (ml/min). The substance in question is typically one that the body needs to remove, such as a waste product or a drug.
Calculation
The renal clearance of a substance can be calculated using the formula:
C = (U x V) / P
where:
- C is the renal clearance
- U is the concentration of the substance in urine
- V is the urine flow rate
- P is the concentration of the substance in plasma
Related Terms
- Glomerular filtration rate (GFR): This is the best overall index of kidney function. It is the amount of filtrate formed by the kidneys per minute.
- Creatinine clearance: This is a test that measures how well creatinine is removed from your blood by your kidneys.
- Inulin clearance: This is a test that measures the kidney's ability to filter and remove waste from the body.
See Also
External links
- Medical encyclopedia article on Renal clearance
- Wikipedia's article - Renal clearance
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