Rapacuronium bromide

From WikiMD.org
Jump to navigation Jump to search

Rapacuronium bromide

Rapacuronium bromide (pronunciation: ra-pa-cu-ro-ni-um bro-mide) is a non-depolarizing neuromuscular-blocking drug or muscle relaxant used in modern anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Etymology

The term "Rapacuronium" is derived from the Latin word 'rapax', meaning 'ravenous' or 'greedy', and 'curare', a term for various plant extract alkaloid arrow poisons used by the indigenous peoples of South America. The suffix '-onium' is a standard ending for all quaternary ammonium muscle relaxants. 'Bromide' refers to the bromide salt form of the drug.

Pharmacology

Rapacuronium bromide acts by competitively binding to nicotinic acetylcholine receptors on the motor end-plate. This antagonizes the action of acetylcholine, resulting in flaccid muscle paralysis.

Related Terms

Side Effects

Common side effects of rapacuronium bromide include hypotension, tachycardia, and bronchospasm. Due to its potential to cause severe bronchospasm, the drug was withdrawn from the market in 2001.

See Also

External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski