Prolymphocyte

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Prolymphocyte

Prolymphocyte (pronunciation: pro-lymph-o-cyte) is a type of white blood cell that is slightly larger than a mature lymphocyte, but smaller than a lymphoblast. It is an intermediate stage in the development of certain types of lymphocytes, specifically B cells and T cells.

Etymology

The term "prolymphocyte" is derived from the Greek words "pro" meaning "before", and "lymphocyte" which refers to a type of white blood cell. Thus, a prolymphocyte is a cell that is in a stage of development before becoming a mature lymphocyte.

Description

Prolymphocytes have a high nucleus-to-cytoplasm ratio, with a prominent nucleolus and a slightly basophilic cytoplasm. They are typically found in the bone marrow, but can also be present in the bloodstream in certain conditions, such as prolymphocytic leukemia.

Related Terms

  • Lymphocyte: A type of white blood cell that is part of the immune system. There are two main types of lymphocytes: B cells and T cells.
  • Lymphoblast: An immature cell that can develop into a lymphocyte.
  • Prolymphocytic leukemia: A rare type of leukemia characterized by an excess of prolymphocytes in the blood.
  • Nucleus-to-cytoplasm ratio: A measure used in cytology to assess the size of a cell's nucleus compared to its cytoplasm.
  • Nucleolus: A small, dense structure in the nucleus of a cell where ribosomal RNA is produced.
  • Basophilic: Referring to cells or tissues that stain blue or purple with basic dyes.

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