Prevotella intermedia
Prevotella intermedia (pronunciation: preh-voh-tell-uh in-ter-mee-dee-uh) is a Gram-negative anaerobic bacterium that is often found in the human oral cavity. It is associated with periodontal disease, including both chronic and aggressive periodontitis.
Etymology
The name "Prevotella" is derived from the name of the French bacteriologist, A.R. Prévot. The species name "intermedia" refers to its intermediate position in a biochemical reaction series.
Characteristics
Prevotella intermedia is a non-motile, non-spore-forming, rod-shaped bacterium. It is Gram-negative, meaning it does not retain the crystal violet stain used in the Gram stain procedure. As an anaerobic bacterium, it thrives in environments that lack oxygen.
Pathogenicity
Prevotella intermedia is one of the key pathogens involved in periodontal disease. It is particularly associated with the progression of gingivitis to periodontitis. It has also been implicated in other infections, including pulmonary infections, otitis media, and obstetric and gynecologic infections.
Treatment
Treatment of infections caused by Prevotella intermedia typically involves antibiotics. The bacterium is usually sensitive to metronidazole, amoxicillin, and clindamycin. However, resistance to these and other antibiotics has been reported, so susceptibility testing is often recommended.
See also
External links
- Medical encyclopedia article on Prevotella intermedia
- Wikipedia's article - Prevotella intermedia
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