P300 (neuroscience)

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P300 (neuroscience)

The P300 or P3 is a component of the Event-related potential (ERP) that is elicited in the process of decision making. It is considered to be an endogenous potential, as its occurrence links not to the physical attributes of a stimulus, but to a person's reaction to it.

Pronunciation

The term is pronounced as "P three hundred".

Etymology

The name "P300" refers to the positive polarity (P) and the latency of roughly 300 milliseconds (300) post-stimulus.

Description

The P300 is most commonly elicited in an "oddball" paradigm when a person detects an infrequent target stimulus in a regular stream of non-targets. The P300 wave only occurs if the subject is actively engaged in the task of detecting the targets. Its amplitude varies with the improbability of the targets. Its latency varies with the difficulty of discriminating the target stimulus from the standard stimuli.

Related Terms

  • Event-related potential (ERP): The measured brain response that is the direct result of a specific sensory, cognitive, or motor event.
  • Oddball paradigm: A fundamental experimental design used within psychology research. It involves the presentation of a series of repeated stimuli, randomly interspersed with a deviant stimulus.
  • Endogenous potential: A brain potential that is generated by the brain's internal processing activity, rather than by an external stimulus.

See Also

References

  • Polich, J. (2007). Updating P300: An integrative theory of P3a and P3b. Clinical Neurophysiology, 118(10), 2128-2148.

External links

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