Nitrosamines

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Nitrosamines

Nitrosamines (/naɪˈtroʊsəmiːnz/), also known as N-nitrosamines, are a group of carcinogenic compounds that are formed by the chemical reaction of nitrites and secondary amines.

Etymology

The term "Nitrosamines" is derived from the words "nitroso", referring to the nitroso functional group, and "amines", which are organic compounds and functional groups that contain a basic nitrogen atom with a lone pair.

Formation and Occurrence

Nitrosamines are commonly formed in an acidic environment where nitrites and amines are present. They are often found in various food products, especially those that are cured, smoked, or fermented. Nitrosamines can also be found in tobacco smoke, certain cosmetics, and in some pharmaceuticals.

Health Effects

Exposure to Nitrosamines has been linked to various types of cancer, including lung, esophageal, and oral cancers. They are classified as a probable human carcinogen by the International Agency for Research on Cancer (IARC).

Related Terms

  • Nitrites: Inorganic compounds that can react with amines to form nitrosamines.
  • Amines: Organic compounds and functional groups that contain a basic nitrogen atom with a lone pair.
  • Carcinogen: Any substance that promotes the formation of cancer.
  • International Agency for Research on Cancer (IARC): A specialized agency of the World Health Organization that promotes international collaboration in cancer research.

External links

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