Moyamoya disease

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Moyamoya disease (pronunciation: /moʊjəˈmoʊjə/) is a rare, progressive cerebrovascular disorder characterized by the narrowing or occlusion of the internal carotid artery and the arteries that branch from it. The term "moyamoya" means "puff of smoke" in Japanese, reflecting the appearance of the tangle of tiny vessels formed to compensate for the blockage.

Etymology

The term "moyamoya" was first used by Japanese researchers in the 1960s. It is derived from the Japanese words "moya" (meaning "hazy") and "moya moya" (meaning "puff of smoke"), which describe the appearance of the angiogram images of the affected vessels.

Symptoms

Symptoms of Moyamoya disease can vary and are usually related to reduced blood flow to the brain. They may include transient ischemic attacks (TIAs), stroke, hemorrhage, seizures, and cognitive decline.

Diagnosis

Diagnosis of Moyamoya disease typically involves neuroimaging techniques such as MRI and angiography. These tests can reveal the characteristic narrowing of the arteries and the formation of small, fragile vessels.

Treatment

Treatment for Moyamoya disease often involves surgery to restore blood flow to the brain. This can include direct bypass surgery or indirect procedures that encourage the growth of new blood vessels.

Prognosis

The prognosis for individuals with Moyamoya disease varies. Some people may experience a slow progression of symptoms, while others may have a more rapid onset of stroke and cognitive decline. Early diagnosis and treatment can improve the prognosis.

See also

External links

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