Membranous glomerulonephritis

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Membranous glomerulonephritis (pronunciation: mem-bray-nus glo-mer-u-lo-nef-ri-tis) is a kidney disease characterized by changes in the parts of the kidneys that help filter waste and fluids. The disease can lead to nephrotic syndrome, which causes significant protein in the urine and low blood protein levels.

Etymology

The term "Membranous glomerulonephritis" is derived from the Latin membrana, meaning "membrane", and glomerulus, referring to the tiny filtering units in the kidneys. The suffix "-itis" is from the Greek -itis, used in medical terminology to denote inflammation.

Symptoms

Symptoms of membranous glomerulonephritis may include edema (swelling), particularly in the legs and ankles, foamy urine due to excess protein (proteinuria), and weight gain due to fluid retention.

Causes

Membranous glomerulonephritis can be caused by various conditions, including autoimmune diseases such as lupus, infections such as hepatitis B, and certain medications. However, in many cases, the cause is unknown (idiopathic membranous glomerulonephritis).

Diagnosis

Diagnosis of membranous glomerulonephritis typically involves urine tests to check for protein, blood tests to assess kidney function, and a kidney biopsy to confirm the diagnosis and determine the cause.

Treatment

Treatment for membranous glomerulonephritis aims to reduce symptoms, slow the progression of the disease, and treat any underlying conditions. This may involve medications to reduce the immune system's activity (immunosuppressants), medications to control blood pressure and reduce proteinuria (ACE inhibitors or ARBs), and treatment for any underlying conditions.

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