Matrix (biology)

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Biological matrix overview



General Information
Latin
Greek
TA98
TA2
FMA
Details
System
Artery
Vein
Nerve
Lymphatic drainage
Precursor
Function Structural support
Identifiers
Clinical significance
Notes


The matrix in biology refers to the material or tissue in animal or plant cells, in which more specialized structures are embedded. It is a complex and dynamic environment that provides structural and biochemical support to the surrounding cells.

Types of Biological Matrices

Extracellular Matrix

The extracellular matrix (ECM) is a three-dimensional network of extracellular macromolecules such as collagen, enzymes, and glycoproteins that provide structural and biochemical support to surrounding cells. The ECM is involved in many important functions, including cell adhesion, cell-to-cell communication, and differentiation.

Intracellular Matrix

The intracellular matrix refers to the cytosol and the organelles within a cell. It is the site of many metabolic processes and provides a medium for the movement of ions, molecules, and organelles within the cell.

Bone Matrix

The bone matrix is the intercellular substance of bone tissue, consisting of collagen fibers, ground substance, and inorganic bone salts. It provides strength and rigidity to bones.

Cartilage Matrix

The cartilage matrix is composed of collagen fibers and proteoglycans, providing a smooth surface for joint movement and acting as a cushion between bones.

Functions of the Matrix

The matrix plays a crucial role in:

  • Providing structural support to tissues and organs.
  • Facilitating cell adhesion and communication.
  • Regulating cell growth, movement, and differentiation.
  • Serving as a reservoir for growth factors and cytokines.

Matrix in Disease

Alterations in the matrix can lead to various diseases and disorders. For example, excessive deposition of ECM components can result in fibrosis, while degradation of the matrix can lead to arthritis and other degenerative diseases.

See Also

References



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Contributors: Prab R. Tumpati, MD