List of antiandrogens

From Food & Medicine Encyclopedia

Antiandrogens are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body. They are used in the treatment of various conditions, such as prostate cancer, androgenetic alopecia (hair loss), acne, and hirsutism. This article provides a list of antiandrogens, categorized by their mechanism of action.

Types of Antiandrogens[edit]

Androgen Receptor Antagonists[edit]

Androgen receptor antagonists directly block the androgen receptor, preventing androgens from activating it.

5α-Reductase Inhibitors[edit]

5α-Reductase inhibitors prevent the conversion of testosterone to the more potent androgen, dihydrotestosterone (DHT), in certain tissues.

Gonadotropin-Releasing Hormone (GnRH) Analogues[edit]

GnRH analogues suppress the production of androgens by inhibiting the release of gonadotropins.

CYP17 Inhibitors[edit]

CYP17 inhibitors block the enzyme CYP17A1, which is involved in the production of androgens.

Uses of Antiandrogens[edit]

Antiandrogens are used in the treatment of various conditions, including:

See Also[edit]

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List of antiandrogens[edit]

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