Intestinal pseudo-obstruction

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Intestinal Pseudo-obstruction

Intestinal pseudo-obstruction (pronounced as in-tuh-stuh-nuhl soo-doh-uhb-struhk-shuhn) is a clinical syndrome characterized by symptoms suggesting mechanical bowel obstruction in the absence of any obstructive lesions. This condition is often chronic and can be debilitating, leading to significant impairment in the quality of life.

Etymology

The term "Intestinal pseudo-obstruction" is derived from the Greek words "enteron" (intestine), "pseudo" (false), and "obstruction" (blockage). It refers to a condition that mimics the symptoms of a true intestinal obstruction but without any physical blockage.

Symptoms

Symptoms of intestinal pseudo-obstruction may include abdominal pain, nausea, vomiting, diarrhea, and constipation. These symptoms can be intermittent or constant, and their severity can vary from mild to severe.

Causes

Intestinal pseudo-obstruction can be caused by a variety of conditions that affect the nerves, muscles, or interstitial cells of Cajal in the gastrointestinal tract. These conditions can be either primary (idiopathic) or secondary to other diseases such as diabetes, scleroderma, or Parkinson's disease.

Diagnosis

Diagnosis of intestinal pseudo-obstruction is often challenging due to the lack of specific diagnostic criteria. It is usually based on the clinical presentation, exclusion of mechanical obstruction, and findings on radiological, endoscopic, and manometric studies.

Treatment

Treatment of intestinal pseudo-obstruction is primarily symptomatic and supportive. It may include dietary modifications, medications to improve gut motility, and in severe cases, enteral nutrition or parenteral nutrition. Surgical intervention may be considered in refractory cases.

See also

External links

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