IgG4-related ophthalmic disease
IgG4-related ophthalmic disease (pronounced as "I-G-G-four-related ophthalmic disease") is a subtype of IgG4-related disease, a systemic condition characterized by tumefactive lesions and often elevated serum IgG4 concentrations.
Etymology
The term "IgG4-related ophthalmic disease" is derived from the name of the antibody involved, IgG4, and the area it affects, the eye and its associated structures.
Definition
IgG4-related ophthalmic disease is a condition where the body's immune system produces an excess of IgG4 antibodies, leading to inflammation and fibrosis in the eye and surrounding tissues. This can result in a variety of symptoms, including redness, swelling, and vision problems.
Symptoms
Symptoms of IgG4-related ophthalmic disease can vary widely, but often include redness, swelling, pain, and vision problems. In severe cases, it can lead to blindness.
Diagnosis
Diagnosis of IgG4-related ophthalmic disease typically involves a combination of clinical examination, imaging studies, and laboratory tests. The presence of elevated serum IgG4 concentrations is a key diagnostic criterion, although it is not specific for this condition.
Treatment
Treatment for IgG4-related ophthalmic disease typically involves the use of corticosteroids to reduce inflammation and suppress the immune response. In severe cases, other immunosuppressive drugs may be used.
Prognosis
The prognosis for IgG4-related ophthalmic disease is generally good with appropriate treatment, although the condition can recur. Long-term monitoring is typically required to manage the condition effectively.
See also
External links
- Medical encyclopedia article on IgG4-related ophthalmic disease
- Wikipedia's article - IgG4-related ophthalmic disease
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