IgG4
IgG4
IgG4 (/aɪdʒiːfɔːr/), also known as Immunoglobulin G4, is a type of antibody that is part of the immune system. It is one of the four subclasses of Immunoglobulin G (IgG), the others being IgG1, IgG2, and IgG3.
Etymology
The term "IgG4" is derived from "Immunoglobulin G subclass 4". Immunoglobulins are a class of proteins in the immune system that function as antibodies. The "G" in IgG stands for "gamma", referring to the type of heavy chain found in this class of antibodies. The "4" refers to the subclass number.
Function
IgG4 antibodies are involved in immune responses and are known for their ability to carry out immune tolerance, a process that prevents the immune system from attacking the body's own cells. They are also involved in responses to some types of allergens and parasites.
Related Terms
- IgG4-related disease: A systemic condition characterized by the infiltration of IgG4-positive plasma cells in various organs.
- IgG4 deficiency: A condition characterized by lower than normal levels of IgG4 in the blood.
- IgG4 overexpression: A condition characterized by higher than normal levels of IgG4 in the blood.
See Also
External links
- Medical encyclopedia article on IgG4
- Wikipedia's article - IgG4
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