Hypergammaglobulinemia

From WikiMD's medical encyclopedia


Hypergammaglobulinemia
Synonyms
Pronounce N/A
Specialty Immunology
Symptoms Elevated levels of gamma globulins in the blood
Complications Autoimmune diseases, infections
Onset Varies depending on underlying cause
Duration Chronic
Types N/A
Causes Chronic infections, autoimmune disorders, liver disease, monoclonal gammopathy
Risks
Diagnosis Blood test showing elevated immunoglobulins
Differential diagnosis Monoclonal gammopathy of undetermined significance, multiple myeloma, chronic lymphocytic leukemia
Prevention
Treatment Address underlying cause, immunosuppressive therapy
Medication Corticosteroids, immunosuppressants
Prognosis Depends on underlying condition
Frequency Common in certain populations with chronic conditions
Deaths N/A


Hypergammaglobulinemia is a condition characterized by an excess of gamma globulins in the blood. Gamma globulins are a type of protein produced by the immune system to help fight infections. Hypergammaglobulinemia can be a sign of various underlying conditions, including chronic infections, autoimmune diseases, and certain types of cancer.

Causes

Hypergammaglobulinemia can be caused by a variety of conditions, including:

Symptoms

The symptoms of hypergammaglobulinemia can vary depending on the underlying cause. They may include:

  • Fatigue
  • Joint pain
  • Swollen lymph nodes
  • Recurrent infections

Diagnosis

Hypergammaglobulinemia is typically diagnosed through a blood test that measures the levels of gamma globulins in the blood. Additional tests may be needed to determine the underlying cause.

Treatment

Treatment for hypergammaglobulinemia typically involves addressing the underlying cause. This may involve antibiotics for infections, immunosuppressive drugs for autoimmune diseases, or chemotherapy for cancer.

See also

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Contributors: Prab R. Tumpati, MD