Hyperestrogenism

Hyperestrogenism
Synonyms	Estrogen excess, Estrogen dominance
Pronounce	N/A
Specialty	N/A
Symptoms	Breast tenderness, menstrual irregularities, weight gain, mood swings, fatigue
Complications	Endometrial hyperplasia, breast cancer, thromboembolism
Onset	Can occur at any age, often during puberty, pregnancy, or menopause
Duration	Variable, depending on cause
Types	N/A
Causes	Hormone replacement therapy, obesity, polycystic ovary syndrome, liver disease
Risks	Obesity, sedentary lifestyle, genetic predisposition
Diagnosis	Blood test for estrogen levels, pelvic ultrasound, endometrial biopsy
Differential diagnosis	Hypothyroidism, hyperprolactinemia, adrenal disorders
Prevention	N/A
Treatment	Lifestyle modification, medication such as aromatase inhibitors, surgery in severe cases
Medication	Aromatase inhibitors, selective estrogen receptor modulators
Prognosis	N/A
Frequency	Common, especially in women
Deaths	N/A

Hyperestrogenism is a medical condition characterized by an excessive amount of estrogen in the body. This condition can occur in both men and women, and can lead to a variety of health problems.

Causes

Hyperestrogenism can be caused by a variety of factors. These include:

• Hormone replacement therapy: This is a common cause of hyperestrogenism in women who are undergoing menopause. The therapy involves taking estrogen to help alleviate the symptoms of menopause, but it can also lead to an excess of estrogen in the body.
• Obesity: Fat cells produce estrogen, so people who are overweight or obese may have higher levels of estrogen in their bodies.
• Certain medications: Some drugs, such as certain types of birth control pills, can increase estrogen levels.
• Tumors: Certain types of tumors, particularly those in the ovaries or adrenal glands, can produce excess estrogen.

Symptoms

The symptoms of hyperestrogenism can vary depending on the individual and the underlying cause of the condition. However, common symptoms can include:

• In women: heavy or irregular periods, breast tenderness, and an increased risk of breast and uterine cancer.
• In men: gynecomastia (enlarged breasts), erectile dysfunction, and a decreased sex drive.

Treatment

Treatment for hyperestrogenism typically involves addressing the underlying cause of the condition. This can include changing medications, losing weight, or treating any tumors that may be present. In some cases, medication to block the effects of estrogen may also be prescribed.

See also

• Estrogen
• Hormone replacement therapy
• Obesity
• Gynecomastia

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