Hexamidine
Hexamidine is a type of antiseptic that is often used in the treatment of various skin diseases and infections. It is a synthetic compound that has been found to be effective against a wide range of microorganisms, including both bacteria and fungi.
History
Hexamidine was first synthesized in the mid-20th century as part of a broader effort to develop new and more effective antiseptics. It quickly gained recognition for its broad-spectrum antimicrobial activity and its relative lack of toxicity, which made it a popular choice for use in a variety of medical and non-medical settings.
Mechanism of Action
Hexamidine works by disrupting the cell membrane of microorganisms, which leads to cell death. It is particularly effective against Gram-positive bacteria, but it also has activity against some Gram-negative bacteria and fungi.
Uses
Hexamidine is used in a variety of medical and non-medical settings. In medicine, it is often used as a topical antiseptic for the treatment of skin infections and wounds. It is also used in some over-the-counter products, such as skin cleansers and wound dressings.
In non-medical settings, hexamidine is often used as a disinfectant. It is commonly found in products used for cleaning and disinfecting surfaces in hospitals and other healthcare facilities.
Side Effects
Like all medications, hexamidine can cause side effects. The most common side effects are skin irritation and allergic reactions. However, these side effects are generally mild and go away on their own after the medication is discontinued.
See Also
References
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Contributors: Prab R. Tumpati, MD