Helen Blau

American scientist specializing in stem cell biology

Helen Blau in 2013

Helen Margaret Blau is an American scientist renowned for her pioneering work in the field of stem cell biology. She is a professor at Stanford University and the director of the Baxter Laboratory for Stem Cell Biology. Her research has significantly advanced the understanding of cellular plasticity and the potential for regenerative medicine.

Early life and education

Helen Blau was born in New York City. She pursued her undergraduate studies at University of York in the United Kingdom, where she developed an interest in biology. She later completed her Ph.D. at Harvard University, focusing on molecular biology and genetics.

Career

Blau began her academic career at Stanford University, where she joined the faculty and established her laboratory. Her early work focused on the mechanisms of cell differentiation and the potential for reprogramming differentiated cells to a pluripotent state. This research laid the groundwork for the development of induced pluripotent stem cells (iPSCs).

Research contributions

Blau's research has been instrumental in demonstrating the plasticity of differentiated cells. Her laboratory was among the first to show that the environment of a cell can influence its fate, leading to the concept of "nuclear reprogramming." This work has implications for regenerative medicine, as it suggests that adult cells can be reprogrammed to repair damaged tissues.

Blau has also contributed to the understanding of muscle regeneration and the role of stem cells in muscle repair. Her studies on the dystrophin gene and its role in muscular dystrophy have provided insights into potential therapeutic approaches for this group of diseases.

Awards and honors

Helen Blau has received numerous awards for her contributions to science, including election to the National Academy of Sciences and the American Academy of Arts and Sciences. She has been recognized for her innovative research and leadership in the field of stem cell biology.

Personal life

Blau is married and has two children. She is an advocate for women in science and has mentored many young scientists throughout her career.

Related pages

• Stem cell
• Regenerative medicine
• Induced pluripotent stem cell
• Muscular dystrophy