HOXC10

HOXC10

Symbol	HOXC10
HGNC ID	5115
Alternative symbols	–
Entrez Gene	–
OMIM	–
RefSeq	–
UniProt	–
Chromosome	12q13.13
Locus supplementary data	–

HOXC10 is a gene that encodes a homeobox protein involved in the regulation of developmental processes. It is part of the HOX gene family, which plays a crucial role in embryonic development and the anterior-posterior axis formation.

Function

The HOXC10 gene is a member of the homeobox family of genes, which are known for their role in regulating patterns of anatomical development (morphogenesis) in animals, fungi, and plants. The protein encoded by HOXC10 is a transcription factor that binds to specific DNA sequences, thereby controlling the expression of other genes. This gene is particularly important in the development of the spinal cord, limbs, and urogenital system.

Clinical Significance

Mutations or dysregulation of the HOXC10 gene have been associated with various developmental disorders and cancers. Studies have shown that abnormal expression of HOXC10 may contribute to the progression of certain types of breast cancer and ovarian cancer.

Research

Research on HOXC10 continues to explore its role in oncogenesis and its potential as a biomarker for certain cancers. Understanding the mechanisms by which HOXC10 influences cell proliferation and differentiation could lead to new therapeutic targets.

See Also

• Homeobox
• HOX gene
• Transcription factor
• Embryonic development

External Links

• HOXC10 Gene - NCBI
• GeneCards: HOXC10