Excess ovarian androgen release syndrome

Excess ovarian androgen release syndrome
Synonyms	Hyperandrogenism, Polycystic ovary syndrome (PCOS)
Pronounce	N/A
Specialty	N/A
Symptoms	Hirsutism, Acne, Oligomenorrhea, Infertility
Complications	Type 2 diabetes, Cardiovascular disease, Endometrial cancer
Onset	Reproductive age
Duration	Chronic
Types	N/A
Causes	Genetic predisposition, Insulin resistance
Risks	Obesity, Family history
Diagnosis	Clinical evaluation, Blood tests for androgen levels, Ultrasound
Differential diagnosis	Congenital adrenal hyperplasia, Cushing's syndrome, Androgen-secreting tumors
Prevention	N/A
Treatment	Lifestyle modification, Oral contraceptives, Anti-androgens, Metformin
Medication	Spironolactone, Flutamide, Eflornithine
Prognosis	N/A
Frequency	Affects approximately 5-10% of women of reproductive age
Deaths	N/A

Excess ovarian androgen release syndrome (EOARS) is a medical condition characterized by the overproduction of androgens by the ovaries. This condition can lead to a variety of symptoms and is often associated with other endocrine disorders.

Symptoms

The symptoms of EOARS can vary widely but often include:

• Hirsutism (excessive hair growth in areas where hair is normally minimal or absent)
• Acne
• Alopecia (hair loss)
• Menstrual irregularities, such as oligomenorrhea or amenorrhea
• Infertility

Causes

EOARS is typically caused by an imbalance in the endocrine system, leading to the ovaries producing an excess amount of androgens. This can be due to:

• Polycystic ovary syndrome (PCOS)
• Congenital adrenal hyperplasia (CAH)
• Ovarian tumors
• Cushing's syndrome

Diagnosis

The diagnosis of EOARS involves a combination of:

• Clinical evaluation of symptoms
• Blood tests to measure levels of testosterone, androstenedione, and dehydroepiandrosterone sulfate (DHEAS)
• Imaging studies such as ultrasound or MRI to assess the ovaries and adrenal glands

Treatment

Treatment for EOARS depends on the underlying cause and may include:

• Hormonal therapy to regulate androgen levels
• Oral contraceptives to manage menstrual irregularities
• Anti-androgens such as spironolactone or flutamide
• Lifestyle changes, including diet and exercise
• Surgery in cases of ovarian tumors

Related Conditions

EOARS is often associated with other conditions, including:

• Polycystic ovary syndrome (PCOS)
• Congenital adrenal hyperplasia (CAH)
• Hyperandrogenism
• Hirsutism

See Also

• Polycystic ovary syndrome
• Congenital adrenal hyperplasia
• Hyperandrogenism
• Hirsutism
• Endocrine system

External Links

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