Etelcalcetide
Etelcalcetide
Etelcalcetide (pronounced as et-el-kal-se-tide) is a medication used in the treatment of secondary hyperparathyroidism associated with chronic kidney disease.
Etymology
The name "Etelcalcetide" is derived from the chemical structure of the drug. "Etel" is a prefix used in pharmacology to denote a drug's synthetic origin, while "calcet" refers to the drug's action on calcium levels in the body, and "tide" is a common suffix for peptides, indicating the drug's peptide structure.
Usage
Etelcalcetide is used to lower parathyroid hormone (PTH) levels in adults with chronic kidney disease who are on dialysis. It works by binding to and activating the calcium-sensing receptor on the parathyroid gland, which decreases PTH secretion, serum calcium levels, and phosphate levels.
Dosage and Administration
Etelcalcetide is administered intravenously at the end of each hemodialysis session. The dosage is individualized and adjusted based on the patient's parathyroid hormone levels.
Side Effects
Common side effects of Etelcalcetide include nausea, vomiting, diarrhea, and hypocalcemia (low calcium levels). Severe hypocalcemia can lead to serious complications such as arrhythmia and seizures.
Related Terms
- Secondary hyperparathyroidism
- Chronic kidney disease
- Parathyroid hormone
- Calcium-sensing receptor
- Dialysis
- Hypocalcemia
External links
- Medical encyclopedia article on Etelcalcetide
- Wikipedia's article - Etelcalcetide
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