Epstein–Barr virus infection

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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W8MD medical weight loss NYC and sleep center NYC

Epstein–Barr virus infection
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Fever, sore throat, swollen lymph nodes, fatigue
Complications	Mononucleosis, Burkitt's lymphoma, nasopharyngeal carcinoma
Onset	Typically in adolescence or young adulthood
Duration	Symptoms usually last 2 to 4 weeks
Types	N/A
Causes	Epstein–Barr virus (EBV)
Risks	Close contact with infected individuals, immunocompromised state
Diagnosis	Serology, PCR testing
Differential diagnosis	Cytomegalovirus infection, streptococcal pharyngitis
Prevention	Avoiding sharing drinks and personal items, good hygiene practices
Treatment	Supportive care, analgesics, antipyretics
Medication	None specific; symptomatic treatment
Prognosis	Generally good; most recover fully
Frequency	Very common; most people are infected at some point in their lives
Deaths	N/A

Epstein–Barr virus infection (also known as EBV infection) is a common viral infection that can lead to several diseases, including infectious mononucleosis, certain types of cancer, and multiple sclerosis. The virus is named after the two researchers, Michael Epstein and Yvonne Barr, who first discovered and documented it in the mid-20th century.

Introduction

The Epstein–Barr virus (EBV) is a member of the herpesvirus family, which includes other well-known viruses such as herpes simplex virus (HSV) and varicella-zoster virus (VZV). EBV is one of the most common viruses worldwide, with over 90% of adults having been infected at some point in their lives.

Transmission

EBV is primarily transmitted through bodily fluids, particularly saliva. This has led to EBV being colloquially known as the "kissing disease". Other methods of transmission include blood transfusions, organ transplants, and from mother to child during childbirth.

Symptoms and Diseases

While many people infected with EBV will show no symptoms, others may develop infectious mononucleosis, also known as "mono" or "the kissing disease". Symptoms of mono include fatigue, fever, inflamed throat, swollen lymph nodes, and an enlarged spleen. In addition to mono, EBV is also associated with several types of cancer, including Hodgkin's lymphoma, Burkitt's lymphoma, nasopharyngeal carcinoma, and gastric cancer. It is also linked to autoimmune diseases such as multiple sclerosis and rheumatoid arthritis.

Diagnosis and Treatment

Diagnosis of EBV infection is typically done through a blood test, which can detect antibodies against the virus. Treatment is usually supportive, as there is currently no specific antiviral treatment for EBV. Rest, hydration, and over-the-counter pain relievers can help manage symptoms.

Prevention

There is currently no vaccine available for EBV, although research is ongoing. Prevention strategies primarily involve avoiding close contact with infected individuals and practicing good hygiene.

See Also

• Infectious mononucleosis
• Herpesvirus
• Cancer
• Autoimmune disease

References

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