Eosinophilic oesophagitis

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Eosinophilic Oesophagitis

Eosinophilic oesophagitis (pronounced: ee-oh-sin-oh-fil-ik ee-sof-uh-jie-tis), often abbreviated as EoE, is a chronic, immune system disease in which a type of white blood cell, the eosinophil, accumulates in the oesophagus and persists despite acid-blocking medicine. The condition may be associated with other diseases such as asthma and allergic rhinitis.

Etymology

The term "eosinophilic oesophagitis" is derived from three Greek words: "eosin," which refers to the rose-coloured stain of eosinophils, a type of disease-fighting white blood cell; "philic," which means loving, as these cells are attracted to areas of inflammation; and "oesophagitis," which refers to inflammation of the oesophagus.

Symptoms

Symptoms of eosinophilic oesophagitis may include difficulty swallowing (dysphagia), food impaction, and heartburn. In children, symptoms may also include feeding disorders and poor growth.

Diagnosis

Diagnosis of eosinophilic oesophagitis involves endoscopy and biopsy of the oesophagus. The presence of a high number of eosinophils in the oesophagus, even after acid-blocking medicine, is a key indicator of the condition.

Treatment

Treatment options for eosinophilic oesophagitis include dietary changes, topical corticosteroids, and dilation of the oesophagus. In some cases, immunotherapy may be considered.

Related Terms

External links

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