Controlled clinical trial
Controlled Clinical Trial
A Controlled Clinical Trial (pronunciation: /kənˈtroʊld ˈklɪnɪkəl traɪəl/) is a type of Clinical Trial that involves the use of a control group and an experimental group to compare the effects of a specific intervention or treatment.
Etymology
The term "Controlled Clinical Trial" is derived from the English words "control", "clinical", and "trial". "Control" (from the Latin contrarotulus, a counter roll or register) refers to the use of a standard or benchmark against which other conditions can be compared. "Clinical" (from the Greek klinike, relating to the bed) refers to the observation and treatment of actual patients. "Trial" (from the Old French trial, an act of testing or proving) refers to a test of the performance, qualities, or suitability of someone or something.
Definition
A Controlled Clinical Trial is a research study conducted to determine the effectiveness of a new drug or treatment in humans. It involves the random allocation of participants into two or more groups: the experimental group, which receives the intervention or treatment under investigation, and the control group, which receives a placebo or the standard treatment. The results of the two groups are then compared to determine if the new treatment is more effective.
Related Terms
- Randomized Controlled Trial: A type of controlled clinical trial where participants are randomly assigned to either the experimental group or the control group.
- Placebo: A substance or treatment which is designed to have no therapeutic value. In a controlled clinical trial, it is given to the control group to compare the effects with the experimental group.
- Blind Trial: A trial in which the participants do not know whether they are in the experimental group or the control group. This is done to prevent bias in the results.
- Double-Blind Trial: A trial in which neither the participants nor the researchers know who is in the experimental group and who is in the control group. This is done to prevent both participant and researcher bias.
External links
- Medical encyclopedia article on Controlled clinical trial
- Wikipedia's article - Controlled clinical trial
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