Compound heterozygosity
Compound heterozygosity (pronunciation: /kɒmpaʊnd hɛtərəʊzaɪgəsɪti/) is a genetic condition where an individual has inherited different forms of a particular gene from each parent.
Etymology
The term "compound heterozygosity" is derived from the words "compound", which means composed of two or more parts, and "heterozygosity", which refers to the presence of different alleles at a particular genetic locus in an organism.
Definition
Compound heterozygosity is a condition that occurs when two different mutations are found at a particular gene locus, one on each chromosome of a pair. The individual is a compound heterozygote, having inherited two different mutant alleles for a particular gene, one from each parent. This is different from a homozygous mutation, where the same mutation is found on both chromosomes.
Related Terms
- Heterozygous: An individual is heterozygous at a gene locus when its cells contain two different alleles of a gene.
- Homozygous: An individual is homozygous at a gene locus when identical alleles of the gene are present on both homologous chromosomes.
- Allele: An allele is one of two or more versions of a gene that are found at the same place on a chromosome.
- Mutation: A mutation is a change in the DNA sequence of a gene.
- Gene: A gene is a unit of heredity which is transferred from a parent to offspring and is held to determine some characteristic of the offspring.
See Also
External links
- Medical encyclopedia article on Compound heterozygosity
- Wikipedia's article - Compound heterozygosity
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