Coagulation disorder
Coagulation Disorder
Coagulation disorder (pronunciation: koh-ag-yuh-ley-shuhn dis-awr-der) is a medical condition that affects the body's ability to form blood clots and stop bleeding.
Etymology
The term "coagulation" comes from the Latin word "coagulare," which means "to curdle." "Disorder" is derived from the Old French "desordre," meaning "lack of order or sequence."
Definition
Coagulation disorders are a group of conditions that cause abnormal clotting and bleeding. These disorders can either cause excessive clotting (hypercoagulability) or insufficient clotting (hypocoagulability).
Types
There are several types of coagulation disorders, including:
- Hemophilia: A genetic disorder that impairs the body's ability to make blood clots.
- Von Willebrand disease: A genetic disorder caused by missing or defective von Willebrand factor, a clotting protein.
- Thrombophilia: A group of disorders characterized by a tendency to form excessive and potentially harmful blood clots.
- Disseminated intravascular coagulation (DIC): A serious disorder in which the proteins that control blood clotting become overactive.
Symptoms
Symptoms of coagulation disorders can vary depending on the specific disorder, but may include:
- Unexplained bleeding or bruising
- Heavy menstrual periods
- Frequent nosebleeds
- Prolonged bleeding from minor cuts or injuries
- Blood in urine or stool
Diagnosis
Diagnosis of coagulation disorders typically involves blood tests to measure clotting factor levels. These may include a prothrombin time (PT) test, an activated partial thromboplastin time (aPTT) test, or a thrombin time (TT) test.
Treatment
Treatment for coagulation disorders depends on the specific disorder and its severity. It may involve medications to prevent or dissolve blood clots, replacement of missing clotting factors, or other therapies.
External links
- Medical encyclopedia article on Coagulation disorder
- Wikipedia's article - Coagulation disorder
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