Centrifugal lipodystrophy
Centrifugal Lipodystrophy
Centrifugal Lipodystrophy (pronunciation: sen-tri-fyoo-guhl lipo-distro-fee) is a rare medical condition characterized by the abnormal distribution of fat in the body.
Etymology
The term 'Centrifugal Lipodystrophy' is derived from two words. 'Centrifugal' is a Latin word where 'centrum' means center and 'fugere' means to flee. 'Lipodystrophy' is a Greek word where 'lipos' means fat and 'dystrophy' means abnormal growth or nutrition.
Definition
Centrifugal Lipodystrophy is a type of Lipodystrophy that is characterized by the progressive loss of subcutaneous fat from the extremities towards the center of the body. This condition can be either inherited or acquired.
Symptoms
The symptoms of Centrifugal Lipodystrophy include loss of fat from the arms, legs, and buttocks, and accumulation of fat in the abdomen and neck. Other symptoms may include insulin resistance, hypertriglyceridemia, and hepatic steatosis.
Causes
The exact cause of Centrifugal Lipodystrophy is unknown. However, it is believed to be associated with mutations in certain genes such as AGPAT2, BSCL2, CAV1, and PTRF.
Diagnosis
Diagnosis of Centrifugal Lipodystrophy is based on physical examination, medical history, and laboratory tests. Genetic testing may also be performed to confirm the diagnosis.
Treatment
Treatment for Centrifugal Lipodystrophy is primarily symptomatic and supportive. It may include dietary modifications, exercise, and medications to manage symptoms. In some cases, surgical intervention may be required.
Related Terms
External links
- Medical encyclopedia article on Centrifugal lipodystrophy
- Wikipedia's article - Centrifugal lipodystrophy
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