Localized lipodystrophy
| Localized lipodystrophy | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Loss of adipose tissue in specific areas |
| Complications | Insulin resistance, dyslipidemia |
| Onset | Variable |
| Duration | Chronic |
| Types | N/A |
| Causes | Autoimmune disease, injection site reactions |
| Risks | Diabetes mellitus, HIV treatment |
| Diagnosis | Clinical examination, biopsy |
| Differential diagnosis | Generalized lipodystrophy, lipoatrophy |
| Prevention | Rotating injection sites, monitoring for autoimmune disorders |
| Treatment | Cosmetic surgery, insulin therapy adjustments |
| Medication | N/A |
| Prognosis | Variable, depends on underlying cause |
| Frequency | Rare |
| Deaths | N/A |
Localized lipodystrophy is a medical condition characterized by the loss of fat tissues in specific areas of the body. This condition can be either congenital or acquired. The congenital form is present at birth, while the acquired form develops later in life, often in response to injections, trauma, or other unknown causes.
Symptoms
The primary symptom of localized lipodystrophy is the loss of fat tissue in specific areas of the body. This can result in an uneven or lumpy appearance to the skin. Other symptoms can include muscle weakness, fatigue, and in some cases, insulin resistance and diabetes.
Causes
The exact cause of localized lipodystrophy is unknown. However, it is often associated with injections of certain medications, such as insulin or corticosteroids. Trauma to the area can also trigger the condition. In some cases, it may be related to autoimmune diseases, such as lupus or dermatomyositis.
Diagnosis
Diagnosis of localized lipodystrophy is typically based on the physical appearance of the affected area. In some cases, a biopsy may be performed to confirm the diagnosis. Other tests, such as blood tests or imaging studies, may be used to rule out other conditions.
Treatment
Treatment for localized lipodystrophy is primarily aimed at managing the symptoms and preventing complications. This can include changes to medication regimens, physical therapy, and in some cases, surgical intervention.
See also
References
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Contributors: Prab R. Tumpati, MD