Carl Djerassi

Austrian-American chemist, novelist, and playwright

Carl Djerassi receiving the AIC Gold Medal

Carl Djerassi (October 29, 1923 – January 30, 2015) was an Austrian-American chemist, novelist, and playwright best known for his contribution to the development of oral contraceptive pills. He was a professor of chemistry at Stanford University and a prolific author, having written numerous works of fiction and non-fiction.

Early Life and Education

Carl Djerassi was born in Vienna, Austria, to a Bulgarian father and an Austrian mother. His family fled the Nazi regime in 1938, eventually settling in the United States. Djerassi attended Kenyon College in Ohio, where he earned a bachelor's degree in chemistry. He later completed his Ph.D. in organic chemistry at the University of Wisconsin–Madison.

Scientific Career

Djerassi's most notable scientific achievement was his work on the synthesis of norethisterone, a key ingredient in the first successful oral contraceptive pill. This work was conducted while he was employed at Syntex, a pharmaceutical company in Mexico City.

Development of the Oral Contraceptive

In 1951, Djerassi and his team synthesized norethisterone, a progestin that was more potent than the natural hormone progesterone. This breakthrough was crucial in the development of the oral contraceptive pill, which revolutionized women's reproductive health and had a profound impact on society.

Luis E. Miramontes' patent for norethisterone

Academic Contributions

After his work at Syntex, Djerassi joined the faculty at Stanford University, where he continued his research in organic chemistry. He published over 1,200 scientific papers and was a pioneer in the field of steroid chemistry.

Literary and Artistic Pursuits

In addition to his scientific work, Djerassi was an accomplished writer. He authored several novels, plays, and essays, often exploring themes related to science and ethics. His "science-in-fiction" genre aimed to provide insight into the lives of scientists and the ethical dilemmas they face.

Awards and Honors

Djerassi received numerous awards throughout his career, including the National Medal of Science, the Priestley Medal, and the Wolf Prize in Chemistry. He was also inducted into the National Inventors Hall of Fame.

Personal Life

Djerassi was married three times and had two children. He was an avid art collector and philanthropist, supporting various cultural and scientific institutions.

Legacy

Carl Djerassi's contributions to science and literature have left a lasting impact. His work on the oral contraceptive pill is considered one of the most significant scientific achievements of the 20th century, and his literary works continue to inspire discussions on the intersection of science and society.

Related Pages

• Oral contraceptive pill
• Steroid chemistry
• Stanford University
• National Medal of Science