CUMYL-3TMS-PRINACA

Synthetic cannabinoid

CUMYL-3TMS-PRINACA
INN
Drug class
Routes of administration
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status
CAS Number	1400742-16-6
PubChem	119025276
DrugBank
ChemSpider	52085456
KEGG

CUMYL-3TMS-PRINACA is a synthetic cannabinoid that has been used in scientific research and is known for its potent activity at the cannabinoid receptors. It is a member of the indazole-3-carboxamide family of synthetic cannabinoids, which are often used as active ingredients in designer drugs.

Chemical Structure

Chemical structure of CUMYL-3TMS-PRINACA

CUMYL-3TMS-PRINACA is chemically classified as an indazole-3-carboxamide. Its IUPAC name is 1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide. The compound features a cyanobutyl group attached to the indazole core, which is a common structural motif in many synthetic cannabinoids.

Pharmacology

CUMYL-3TMS-PRINACA acts as a potent agonist at the CB1 and CB2 cannabinoid receptors. These receptors are part of the endocannabinoid system, which plays a role in regulating various physiological processes including mood, appetite, and pain sensation. The high affinity of CUMYL-3TMS-PRINACA for these receptors contributes to its psychoactive effects.

Legal Status

The legal status of CUMYL-3TMS-PRINACA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. It is often included in legislation targeting synthetic cannabinoids and other novel psychoactive substances.

Health Effects

The use of CUMYL-3TMS-PRINACA, like other synthetic cannabinoids, can lead to a range of adverse health effects. These may include tachycardia, hypertension, nausea, vomiting, anxiety, and hallucinations. Severe cases can result in seizures, renal failure, and death.

Synthesis

The synthesis of CUMYL-3TMS-PRINACA involves the reaction of an indazole-3-carboxylic acid derivative with a suitable amine. The process typically requires careful control of reaction conditions to ensure the desired product is obtained with high purity.

Related pages

• Synthetic cannabinoids
• Cannabinoid receptor
• Designer drug