Benzyl chloride
Benzyl chloride, also known as α-chlorotoluene, is an organic compound with the formula C₆H₅CH₂Cl. This colourless liquid is a reactive organochloride that is a widely used chemical building block.
Properties
Benzyl chloride is a colorless liquid with a pungent odor. It is poorly soluble in water but miscible with organic solvents. As an alkyl halide, it is highly reactive, particularly with nucleophiles, and functions as an alkylating agent.
Production
Benzyl chloride is primarily produced by the free-radical halogenation of toluene, with chlorine gas. The reaction is conducted in the presence of a catalyst, such as ferric chloride, under controlled conditions to favor the formation of the benzyl chloride.
Uses
Benzyl chloride is used in the manufacture of other organic compounds, including pharmaceuticals, dyes, and plasticizers. It serves as an intermediate in the synthesis of benzyl alcohol, benzyl quaternary ammonium compounds, and various esters. Benzyl chloride is also employed in the production of benzyl cellulose and as a photographic developer.
Safety
Benzyl chloride is a lachrymator and has been classified as a potential occupational carcinogen. It is highly irritating to the skin, eyes, and respiratory system. Proper handling and safety equipment are essential when working with this chemical.
Environmental Impact
Due to its reactivity and potential for bioaccumulation, benzyl chloride poses a risk to the environment. It is important to prevent its release into the environment and to follow proper disposal procedures for chemical waste.
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Contributors: Prab R. Tumpati, MD