Antimuscarinics
Antimuscarinics
Antimuscarinics (pronunciation: an-tee-mus-ka-rin-iks), also known as anticholinergics, are a group of pharmaceutical compounds that serve to inhibit the activity of the muscarinic acetylcholine receptors. The term "antimuscarinic" derives from the name of the poisonous mushroom Amanita muscaria, from which the compound muscarine, a natural product affecting these receptors, was first isolated.
Mechanism of Action
Antimuscarinics work by blocking the muscarinic acetylcholine receptors. These receptors are found in various parts of the body, including the brain, heart, smooth muscles, and glands. By blocking these receptors, antimuscarinics can reduce muscle spasms, decrease secretions, and have other effects.
Uses
Antimuscarinics are used in the treatment of a variety of conditions, including Parkinson's disease, overactive bladder, COPD, and certain types of poisoning. They can also be used to reduce the side effects of certain other medications.
Side Effects
Common side effects of antimuscarinics include dry mouth, blurred vision, constipation, and confusion. In severe cases, they can cause hallucinations or other serious mental changes.
Related Terms
- Muscarinic acetylcholine receptor
- Cholinergic
- Parasympathetic nervous system
- Sympathetic nervous system
See Also
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